Protein Variants | Comment | Organism |
---|---|---|
additional information | Gap1p mutants, deficient in transport of a subset of amino acids, show that Gap1p inactivation at the plasma membrane does not depend on the presence of either extracellular or intracellular amino acids, but does require active amino acid transport by Gap1p | Saccharomyces cerevisiae |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
L-arginine | 8% cell growth, 25% viability of cells | Saccharomyces cerevisiae | |
L-asparagine | 35% cell growth, 70% viability of cells | Saccharomyces cerevisiae | |
L-citrulline | 1% cell growth, 1% viability of cells | Saccharomyces cerevisiae | |
L-cysteine | 1% cell growth, 1% viability of cells | Saccharomyces cerevisiae | |
L-glutamate | 2% cell growth, 4% viability of cells | Saccharomyces cerevisiae | |
L-glutamine | 18% cell growth, 70% viability of cells | Saccharomyces cerevisiae | |
L-Glycine | 1% cell growth, 1% viability of cells | Saccharomyces cerevisiae | |
L-histidine | 3% cell growth, 1% viability of cells | Saccharomyces cerevisiae | |
L-isoleucine | 2% cell growth, 1% viability of cells | Saccharomyces cerevisiae | |
L-leucine | 34% cell growth, 35% viability of cells | Saccharomyces cerevisiae | |
L-lysine | 1% cell growth, 1% viability of cells | Saccharomyces cerevisiae | |
L-methionine | 16% cell growth, 70% viability of cells | Saccharomyces cerevisiae | |
L-proline | 9% cell growth, 701% viability of cells | Saccharomyces cerevisiae | |
L-serine | 20% cell growth, 25% viability of cells | Saccharomyces cerevisiae | |
L-threonine | 1% cell growth, 1% viability of cells | Saccharomyces cerevisiae | |
L-tryptophan | 4% cell growth, 25% viability of cells | Saccharomyces cerevisiae | |
L-tyrosine | 20% cell growth, 35% viability of cells | Saccharomyces cerevisiae | |
L-valine | 13% cell growth, 10% viability of cells | Saccharomyces cerevisiae | |
additional information | permease activity can be rapidly and reversibly inactivated by the presence of most amino acids, except alanine or phenylalanine, mixtures of amino acids are less toxic than single amino acids, the toxicity appears to be the consequence of uptake of unusually large quantities of a single amino acid | Saccharomyces cerevisiae |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
plasma membrane | - |
Saccharomyces cerevisiae | 5886 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
Gap1p | - |
Saccharomyces cerevisiae |
general amino acid permease | - |
Saccharomyces cerevisiae |