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Literature summary extracted from

  • Liu, J.; Zhu, J.; Tang, L.; Wen, W.; Lv, S.; Yu, R.
    Enhancement of vindoline and vinblastine production in suspension-cultured cells of Catharanthus roseus by artemisinic acid elicitation (2014), World J. Microbiol. Biotechnol., 30, 175-180 .
    View publication on PubMed

Application

EC Number Application Comment Organism
1.14.11.20 synthesis artemisinic acid can be used as a promising elicitor, especially for the production of therapeutically important indole alkaloids Catharanthus roseus
1.14.14.83 synthesis artemisinic acid can be used as a promising elicitor, especially for the production of therapeutically important indole alkaloids Catharanthus roseus
1.14.14.103 synthesis artemisinic acid can be used as a promising elicitor, especially for the production of therapeutically important indole alkaloids Catharanthus roseus
4.1.1.28 synthesis artemisinic acid can be used as a promising elicitor, especially for the production of therapeutically important indole alkaloids Catharanthus roseus

Organism

EC Number Organism UniProt Comment Textmining
1.14.11.20 Catharanthus roseus O04847
-
-
1.14.14.83 Catharanthus roseus Q8VWZ7
-
-
1.14.14.103 Catharanthus roseus
-
-
-
4.1.1.28 Catharanthus roseus P17770
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.11.20 cell suspension culture from leaf Catharanthus roseus
-
1.14.11.20 leaf suspension-cultured cell from leaf Catharanthus roseus
-
1.14.14.83 cell suspension culture from leaf Catharanthus roseus
-
1.14.14.83 leaf suspension-cultured cell from leaf Catharanthus roseus
-
1.14.14.103 cell suspension culture from leaf Catharanthus roseus
-
1.14.14.103 leaf suspension-cultured cell from leaf Catharanthus roseus
-
4.1.1.28 cell suspension culture from leaf Catharanthus roseus
-
4.1.1.28 leaf suspension-cultured cell from leaf Catharanthus roseus
-

Synonyms

EC Number Synonyms Comment Organism
1.14.11.20 D4H
-
 Catharanthus roseus
1.14.14.83 G10H
-
 Catharanthus roseus
1.14.14.83 geraniol 10-hydroxylase
-
 Catharanthus roseus
1.14.14.103 T16H
-
 Catharanthus roseus
1.14.14.103 tabersonine 16-hydroxylase
-
 Catharanthus roseus
4.1.1.28 TDC
-
 Catharanthus roseus
4.1.1.28 Tryptophan decarboxylase
-
 Catharanthus roseus

Expression

EC Number Organism Comment Expression
1.14.11.20 Catharanthus roseus artemisinic acid is able to upregulate the transcriptions of deacetoxyvindoline 4-hydroxylase up
1.14.14.83 Catharanthus roseus artemisinic acid is able to upregulate the transcriptions of geraniol 10-hydroxylase up
1.14.14.103 Catharanthus roseus artemisinic acid is able to upregulate the transcriptions of tabersonine 16-hydroxylase up
4.1.1.28 Catharanthus roseus artemisinic acid is able to upregulate the transcriptions of geraniol 10-hydroxylase up

General Information

EC Number General Information Comment Organism
1.14.11.20 metabolism the enzyme is involved in biosynthesis of terpenoidindole alkaloids Catharanthus roseus
1.14.14.83 metabolism the enzyme is involved in biosynthesis of terpenoid indole alkaloids Catharanthus roseus
1.14.14.103 metabolism the enzyme is involved in biosynthesis of terpenoid indole alkaloids Catharanthus roseus
4.1.1.28 metabolism the enzyme is involved in biosynthesis of terpenoidindole alkaloids Catharanthus roseus