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Literature summary extracted from
- Expression, purification and kinetic properties of human recombinant phospholipase C delta 3 (1997), Acta Biochim. Pol., 44, 221-229.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.4.3 | histone | PLC d1 and PLC d3 | Homo sapiens |  |
| 3.1.4.3 | lysozyme | PLC d1 | Homo sapiens | |
| 3.1.4.3 | Melittin | PLC d1 and PLC d3 | Homo sapiens | |
| 3.1.4.3 | putrescine | PLC d1 | Homo sapiens | |
| 3.1.4.3 | spermidine | PLC d1 | Homo sapiens | |
| 3.1.4.3 | spermine | PLC d1 and PLC d3 | Homo sapiens | |
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.1.4.3 | tranformed in Escherichia coli | Homo sapiens |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.4.3 | Ca2+ | recombinant PLC d3: maximum activity with 0.001 mM, recombinant PLC d1: maximum activity with 0.01 mM | Homo sapiens | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.1.4.3 | 83000 | - |
SDS-PAGE | Homo sapiens |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.4.3 | phosphatidylinositol-bisphosphate + H2O | Homo sapiens | - |
inositol 1,4,5-trisphosphate + 1,2-diacylglycerol | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.4.3 | Homo sapiens | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.1.4.3 | recombinant PLC, cation exchange chromatography, 26fold to homogeneity | Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.1.4.3 | 53.13 | - |
substrate: phosphatidylinositol-4,5-bisphosphate | Homo sapiens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.4.3 | phosphatidylinositol-bisphosphate + H2O | - |
Homo sapiens | inositol 1,4,5-trisphosphate + 1,2-diacylglycerol | - |
? | |
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