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Literature summary extracted from
- Calf-spleen nicotinamide-adenine dinucleotide glycohydrolase (1978), Eur. J. Biochem., 83, 205-214.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.2.2.5 | 2-Hydroxy-3,5-diiodo-benzoic acid | - |
Bos taurus |  |
| 3.2.2.5 | 2-Hydroxy-5-iodo-benzoic acid | - |
Bos taurus | |
| 3.2.2.5 | adenosine 3',5'-monophosphate | not the soluble form | Bos taurus | |
| 3.2.2.5 | salicylic acid | - |
Bos taurus | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.2.2.5 | 0.056 | - |
NAD+ | - |
Bos taurus | |
| 3.2.2.5 | 0.08 | - |
NADP+ | - |
Bos taurus | |
| 3.2.2.5 | 0.1 | - |
dNAD+ | - |
Bos taurus | |
| 3.2.2.5 | 1.3 | - |
NMN | - |
Bos taurus | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.2.2.5 | NAD+ + H2O | Bos taurus | - |
ADPribose + nicotinamide | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.2.2.5 | Bos taurus | - |
calf | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.2.2.5 | dNAD+ + H2O | - |
Bos taurus | ? | - |
? | |
| 3.2.2.5 | NAD+ + H2O | - |
Bos taurus | ADPribose + nicotinamide | - |
? | |
| 3.2.2.5 | NADP+ + H2O | - |
Bos taurus | phospho-ADPribose + nicotinamide | - |
? | |
| 3.2.2.5 | NMN + H2O | - |
Bos taurus | phosphoribose + nicotinamide | - |
? | |
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Release 2023.1 (January 2023)
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