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Literature summary extracted from

  • Stadler, R.M.; Zenk, M.H.
    A revision of the generally accepted pathway for the biosynthesis of the benzyltetrahydroisoquinoline alkaloid reticuline (1990), Liebigs Ann. Chem., 1990, 555-562.
No PubMed abstract available

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.140 S-Adenosyl-L-methionine + (S)-coclaurine Eschscholzia californica pathway for the biosynthesis of the benzyltetrahydroisoquinoline alkaloid reticuline: (S)-norcoclaurine is stereoselectively metabolized to (S)-reticuline via (S)-coclaurine, (S)-N-methylcoclaurine and (S)-3'-hydroxy-N-methylcoclaurine ?
-
 ?
2.1.1.140 S-Adenosyl-L-methionine + (S)-coclaurine Berberis stolonifera pathway for the biosynthesis of the benzyltetrahydroisoquinoline alkaloid reticuline: (S)-norcoclaurine is stereoselectively metabolized to (S)-reticuline via (S)-coclaurine, (S)-N-methylcoclaurine and (S)-3'-hydroxy-N-methylcoclaurine ?
-
 ?
2.1.1.140 S-Adenosyl-L-methionine + (S)-coclaurine Peumus boldus pathway for the biosynthesis of the benzyltetrahydroisoquinoline alkaloid reticuline: (S)-norcoclaurine is stereoselectively metabolized to (S)-reticuline via (S)-coclaurine, (S)-N-methylcoclaurine and (S)-3'-hydroxy-N-methylcoclaurine ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.140 Berberis stolonifera
-
-
-
2.1.1.140 Eschscholzia californica
-
-
-
2.1.1.140 Peumus boldus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.140 cell culture
-
 Eschscholzia californica
-
2.1.1.140 cell culture
-
 Berberis stolonifera
-
2.1.1.140 cell culture
-
 Peumus boldus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.140 S-Adenosyl-L-methionine + (S)-coclaurine
-
 Eschscholzia californica S-Adenosyl-L-homocysteine + N-methylcoclaurine
-
 ?
2.1.1.140 S-Adenosyl-L-methionine + (S)-coclaurine
-
 Berberis stolonifera S-Adenosyl-L-homocysteine + N-methylcoclaurine
-
 ?
2.1.1.140 S-Adenosyl-L-methionine + (S)-coclaurine
-
 Peumus boldus S-Adenosyl-L-homocysteine + N-methylcoclaurine
-
 ?
2.1.1.140 S-Adenosyl-L-methionine + (S)-coclaurine pathway for the biosynthesis of the benzyltetrahydroisoquinoline alkaloid reticuline: (S)-norcoclaurine is stereoselectively metabolized to (S)-reticuline via (S)-coclaurine, (S)-N-methylcoclaurine and (S)-3'-hydroxy-N-methylcoclaurine Eschscholzia californica ?
-
 ?
2.1.1.140 S-Adenosyl-L-methionine + (S)-coclaurine pathway for the biosynthesis of the benzyltetrahydroisoquinoline alkaloid reticuline: (S)-norcoclaurine is stereoselectively metabolized to (S)-reticuline via (S)-coclaurine, (S)-N-methylcoclaurine and (S)-3'-hydroxy-N-methylcoclaurine Berberis stolonifera ?
-
 ?
2.1.1.140 S-Adenosyl-L-methionine + (S)-coclaurine pathway for the biosynthesis of the benzyltetrahydroisoquinoline alkaloid reticuline: (S)-norcoclaurine is stereoselectively metabolized to (S)-reticuline via (S)-coclaurine, (S)-N-methylcoclaurine and (S)-3'-hydroxy-N-methylcoclaurine Peumus boldus ?
-
 ?