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Literature summary extracted from

  • Ting, S.M.; Miller, O.N.; Sellinger, O.Z.
    The metabolism of lactaldehyde: VII. The oxidation of D-lactaldehyde in rat liver (1965), Biochim. Biophys. Acta, 97, 407-415.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.78 iodoacetate
-
 Rattus norvegicus
1.1.1.78 N-ethylmaleimide
-
 Rattus norvegicus
1.1.1.78 p-chloromercuribenzoate
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.78 0.013
-
 DL-lactaldehyde
-
 Rattus norvegicus
1.1.1.78 0.034
-
 NAD+
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.78 methylglyoxal + NADH Rattus norvegicus
-
 (R)-lactaldehyde + NAD+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.78 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.78
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.78 brain
-
 Rattus norvegicus
-
1.1.1.78 heart
-
 Rattus norvegicus
-
1.1.1.78 kidney
-
 Rattus norvegicus
-
1.1.1.78 liver
-
 Rattus norvegicus
-
1.1.1.78 lung
-
 Rattus norvegicus
-
1.1.1.78 skeletal muscle highest activity Rattus norvegicus
-
1.1.1.78 spleen
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.78 DL-glyceraldehyde + NAD+
-
 Rattus norvegicus ?
-
 ?
1.1.1.78 methylglyoxal + NADH
-
 Rattus norvegicus (R)-lactaldehyde + NAD+
-
 r
1.1.1.78 methylglyoxal + NADPH
-
 Rattus norvegicus lactaldehyde + NADP+
-
 ?
1.1.1.78 additional information specific for lactaldehyde Rattus norvegicus ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.78 11
-
 in the oxidation of D-lactaldehyde, increase of reaction rate up to pH 11 Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.78 NAD+
-
 Rattus norvegicus
1.1.1.78 NADH
-
 Rattus norvegicus