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Literature summary extracted from

  • Oesch, F.
    Purification and specificity of a human microsomal epoxide hydratase (1974), Biochem. J., 139, 77-88.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.3.2.9 1-(2-cyanophenyl)-imidazole 2 mM, stimulates Cavia porcellus
3.3.2.9 1-(2-cyanophenyl)-imidazole 2 mM, stimulates Homo sapiens
3.3.2.9 1-(2-cyanophenyl)-imidazole 2 mM, stimulates Rattus norvegicus
3.3.2.9 1-(2-Isopropylphenyl)-imidazole 2 mM, stimulates Cavia porcellus
3.3.2.9 1-(2-Isopropylphenyl)-imidazole 2 mM, stimulates Homo sapiens
3.3.2.9 1-(2-Isopropylphenyl)-imidazole 2 mM, stimulates Rattus norvegicus
3.3.2.9 ethanol 2.7 M, stimulates Cavia porcellus
3.3.2.9 ethanol 2.7 M, stimulates Homo sapiens
3.3.2.9 ethanol 2.7 M, stimulates Rattus norvegicus
3.3.2.9 Metyrapone 2 mM, stimulates Cavia porcellus
3.3.2.9 Metyrapone 2 mM, stimulates Homo sapiens
3.3.2.9 Metyrapone 2 mM, stimulates Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.3.2.9 1,1-diphenyloxirane
-
 Cavia porcellus
3.3.2.9 1,1-diphenyloxirane
-
 Homo sapiens
3.3.2.9 1,1-diphenyloxirane
-
 Rattus norvegicus
3.3.2.9 1-isopropyl-1-phenyloxirane
-
 Cavia porcellus
3.3.2.9 1-isopropyl-1-phenyloxirane
-
 Homo sapiens
3.3.2.9 1-isopropyl-1-phenyloxirane
-
 Rattus norvegicus
3.3.2.9 1-methyl-1-phenyloxirane
-
 Cavia porcellus
3.3.2.9 1-methyl-1-phenyloxirane
-
 Homo sapiens
3.3.2.9 1-methyl-1-phenyloxirane
-
 Rattus norvegicus
3.3.2.9 1-methylcyclohexene oxide
-
 Cavia porcellus
3.3.2.9 1-methylcyclohexene oxide
-
 Homo sapiens
3.3.2.9 3,3,3-trichloropropene oxide
-
 Cavia porcellus
3.3.2.9 3,3,3-trichloropropene oxide
-
 Homo sapiens
3.3.2.9 3,3,3-trichloropropene oxide
-
 Rattus norvegicus
3.3.2.9 3,3,3-trifluoropropene oxide
-
 Cavia porcellus
3.3.2.9 3,3,3-trifluoropropene oxide
-
 Homo sapiens
3.3.2.9 3,3,3-trifluoropropene oxide
-
 Rattus norvegicus
3.3.2.9 3,3-dimethylbutene oxide
-
 Cavia porcellus
3.3.2.9 3,3-dimethylbutene oxide
-
 Homo sapiens
3.3.2.9 3,3-dimethylbutene oxide
-
 Rattus norvegicus
3.3.2.9 3-methylbutene 1,2-oxide
-
 Cavia porcellus
3.3.2.9 3-methylbutene 1,2-oxide
-
 Homo sapiens
3.3.2.9 3-methylbutene 1,2-oxide
-
 Rattus norvegicus
3.3.2.9 3-methylcyclohexene oxide
-
 Cavia porcellus
3.3.2.9 3-methylcyclohexene oxide
-
 Homo sapiens
3.3.2.9 3-methylcyclohexene oxide
-
 Rattus norvegicus
3.3.2.9 3-phenylpropene 1,2-oxide
-
 Cavia porcellus
3.3.2.9 3-phenylpropene 1,2-oxide
-
 Homo sapiens
3.3.2.9 3-phenylpropene 1,2-oxide
-
 Rattus norvegicus
3.3.2.9 cis-2-methyl-1-phenyloxirane
-
 Cavia porcellus
3.3.2.9 cis-2-methyl-1-phenyloxirane
-
 Homo sapiens
3.3.2.9 cis-2-methyl-1-phenyloxirane
-
 Rattus norvegicus
3.3.2.9 cis-stilbene oxide
-
 Cavia porcellus
3.3.2.9 cis-stilbene oxide
-
 Homo sapiens
3.3.2.9 cis-stilbene oxide
-
 Rattus norvegicus
3.3.2.9 Cyclohexene oxide
-
 Cavia porcellus
3.3.2.9 Cyclohexene oxide
-
 Homo sapiens
3.3.2.9 Cyclohexene oxide
-
 Rattus norvegicus
3.3.2.9 indene 1,2-oxide
-
 Cavia porcellus
3.3.2.9 indene 1,2-oxide
-
 Homo sapiens
3.3.2.9 indene 1,2-oxide
-
 Rattus norvegicus
3.3.2.9 m-bromostyrene oxide
-
 Cavia porcellus
3.3.2.9 m-bromostyrene oxide
-
 Homo sapiens
3.3.2.9 m-bromostyrene oxide
-
 Rattus norvegicus
3.3.2.9 m-nitrostyrene oxide
-
 Cavia porcellus
3.3.2.9 m-nitrostyrene oxide
-
 Homo sapiens
3.3.2.9 m-nitrostyrene oxide
-
 Rattus norvegicus
3.3.2.9 methyl-p-epoxymethylbenzoate
-
 Cavia porcellus
3.3.2.9 methyl-p-epoxymethylbenzoate
-
 Homo sapiens
3.3.2.9 methyl-p-epoxymethylbenzoate
-
 Rattus norvegicus
3.3.2.9 n-octene 1,2-oxide
-
 Cavia porcellus
3.3.2.9 n-octene 1,2-oxide
-
 Homo sapiens
3.3.2.9 n-octene 1,2-oxide
-
 Rattus norvegicus
3.3.2.9 naphthalene 1,2-oxide
-
 Cavia porcellus
3.3.2.9 naphthalene 1,2-oxide
-
 Homo sapiens
3.3.2.9 naphthalene 1,2-oxide
-
 Rattus norvegicus
3.3.2.9 p-bromostyrene oxide
-
 Cavia porcellus
3.3.2.9 p-bromostyrene oxide
-
 Homo sapiens
3.3.2.9 p-bromostyrene oxide
-
 Rattus norvegicus
3.3.2.9 p-chlorophenyl 2,3-epoxypropyl ether
-
 Cavia porcellus
3.3.2.9 p-chlorophenyl 2,3-epoxypropyl ether
-
 Homo sapiens
3.3.2.9 p-chlorophenyl 2,3-epoxypropyl ether
-
 Rattus norvegicus
3.3.2.9 p-nitrostyrene oxide
-
 Cavia porcellus
3.3.2.9 p-nitrostyrene oxide
-
 Homo sapiens
3.3.2.9 p-nitrostyrene oxide
-
 Rattus norvegicus
3.3.2.9 p-phenylstyrene oxide
-
 Cavia porcellus
3.3.2.9 p-phenylstyrene oxide
-
 Homo sapiens
3.3.2.9 p-phenylstyrene oxide
-
 Rattus norvegicus
3.3.2.9 propene oxide
-
 Cavia porcellus
3.3.2.9 propene oxide
-
 Homo sapiens
3.3.2.9 propene oxide
-
 Rattus norvegicus
3.3.2.9 styrene oxide
-
 Cavia porcellus
3.3.2.9 styrene oxide
-
 Homo sapiens
3.3.2.9 styrene oxide
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.3.2.9 microsome
-
 Cavia porcellus
-
-
3.3.2.9 microsome
-
 Homo sapiens
-
-
3.3.2.9 microsome
-
 Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
3.3.2.9 Cavia porcellus
-
-
-
3.3.2.9 Homo sapiens
-
-
-
3.3.2.9 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.3.2.9
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.3.2.9 liver
-
 Cavia porcellus
-
3.3.2.9 liver
-
 Homo sapiens
-
3.3.2.9 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.3.2.9 0.118
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.3.2.9 1-methyl-1-phenyloxirane + H2O
-
 Homo sapiens ?
-
 ?
3.3.2.9 cyclohexene oxide + H2O
-
 Homo sapiens ?
-
 ?
3.3.2.9 indene 1,2-oxide + H2O
-
 Homo sapiens ?
-
 ?
3.3.2.9 styrene oxide + H2O
-
 Cavia porcellus styrene glycol
-
 ?
3.3.2.9 styrene oxide + H2O
-
 Homo sapiens styrene glycol
-
 ?
3.3.2.9 styrene oxide + H2O
-
 Rattus norvegicus styrene glycol
-
 ?