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Literature summary extracted from

  • Ariyoshi, N.; Tanaka, M.; Ishii, Y.; Oguri, K.
    Purification and characterization of dog liver microsomal epoxide hydrolase (1994), J. Biochem., 115, 985-990.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.3.2.9 Isoquinoline stimulates Canis lupus familiaris
3.3.2.9 Metyrapone stimulates Canis lupus familiaris

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.3.2.9 1,1,1-Trichloropropene 2,3-oxide
-
 Canis lupus familiaris
3.3.2.9 2-Bromo-4'-nitroacetophenone
-
 Canis lupus familiaris
3.3.2.9 Cyclohexene oxide
-
 Canis lupus familiaris

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.3.2.9 0.17
-
 7-glycidoxycoumarin
-
 Canis lupus familiaris

Organism

EC Number Organism UniProt Comment Textmining
3.3.2.9 Canis lupus familiaris
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.3.2.9 1.98
-
-
 Canis lupus familiaris

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.3.2.9 7-glycidoxycoumarin + H2O
-
 Canis lupus familiaris ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.3.2.9 8
-
-
 Canis lupus familiaris

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.3.2.9 7 10 pH 7.0: about 60% of maximal activity, pH 10.0: about 25% of maximal activity Canis lupus familiaris