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Literature summary extracted from

  • Roberts, E.
    Glutaminase (1960), The Enzymes, 2nd Ed (Boyer, P. D. , Lardy, H. , Myrbäck, K. , eds. ), 4, 285-300.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.1.2 1,2-naphthoquinone 4-sulfonate
-
 Canis lupus familiaris
3.5.1.2 1,4-Naphthoquinone
-
 Canis lupus familiaris
3.5.1.2 1-amino-8-naphthol-2,4-disulfonic acid weak Canis lupus familiaris
3.5.1.2 2,4-dinitro-1-naphthol-7-sulfonic acid i.e. flavianic acid Canis lupus familiaris
3.5.1.2 anthraquinone-1,8-disulfonate
-
 Canis lupus familiaris
3.5.1.2 arsenate 0.5 M, 74% inhibition Sus scrofa
3.5.1.2 bicarbonate 0.5 M, complete inhibition Sus scrofa
3.5.1.2 Bromocresol green
-
 Canis lupus familiaris
3.5.1.2 bromocresol purple
-
 Canis lupus familiaris
3.5.1.2 Cl- 0.5 M, complete inhibition Sus scrofa
3.5.1.2 CN- 0.5 M, complete inhibition Sus scrofa
3.5.1.2 diphosphate 0.1 M, 98% inhibition Sus scrofa
3.5.1.2 Evans blue
-
 Canis lupus familiaris
3.5.1.2 glutamate
-
 Canis lupus familiaris
3.5.1.2 glutamate
-
 Sus scrofa
3.5.1.2 Hg2+ HgCl2 Canis lupus familiaris
3.5.1.2 iodoacetamide
-
 Canis lupus familiaris
3.5.1.2 NEM
-
 Canis lupus familiaris
3.5.1.2 NEM
-
 Sus scrofa
3.5.1.2 NH4+
-
 Canis lupus familiaris
3.5.1.2 NH4+
-
 Sus scrofa
3.5.1.2 nitrite 0.5 M, complete inhibition Sus scrofa
3.5.1.2 p-benzoquinone
-
 Canis lupus familiaris
3.5.1.2 p-mercuribenzoate
-
 Canis lupus familiaris
3.5.1.2 pyruvate 0.5 M, complete inhibition Sus scrofa
3.5.1.2 Tris 0.5 M, complete inhibition Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.2 Canis lupus familiaris
-
-
-
3.5.1.2 Clostridium welchii
-
-
-
3.5.1.2 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.5.1.2
-
 Sus scrofa
3.5.1.2
-
 Canis lupus familiaris

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.1.2 kidney
-
 Sus scrofa
-
3.5.1.2 kidney
-
 Canis lupus familiaris
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.2 alpha-methyl-DL-Gln + H2O
-
 Canis lupus familiaris ?
-
 ?
3.5.1.2 gamma-glutamyl-methylamide + H2O no activity Canis lupus familiaris Glu + N-methylhydroxylamine
-
 ?
3.5.1.2 Gln + H2O
-
 Sus scrofa Glu + NH3
-
 ?
3.5.1.2 Gln + H2O
-
 Canis lupus familiaris Glu + NH3
-
 ?
3.5.1.2 Gln + H2O
-
 Clostridium welchii Glu + NH3
-
 r
3.5.1.2 L-Asn + H2O no activity Canis lupus familiaris L-Asp + NH3
-
 ?
3.5.1.2 L-gamma-glutamyl-hydrazide + H2O
-
 Canis lupus familiaris L-Glu + hydroxyhydrazine
-
 ?
3.5.1.2 L-gamma-glutamyl-methylester + H2O no activity Canis lupus familiaris L-Glu + methanol
-
 ?
3.5.1.2 L-isoglutamine + H2O
-
 Canis lupus familiaris ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.5.1.2 7.9 8.1
-
 Sus scrofa
3.5.1.2 7.9 8.1
-
 Canis lupus familiaris