Any feedback?
Literature summary extracted from
- Oxidative catabolism of uracil by Enterobacter aerogenes (1987), FEMS Microbiol. Lett., 40, 33-36.
No PubMed abstract available
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.17.99.4 | methylene blue | required as electron acceptor | Klebsiella aerogenes |  |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.17.99.4 | cytoplasm | - |
Klebsiella aerogenes | 5737 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.17.99.4 | uracil + acceptor | Klebsiella aerogenes | reaction in two-step oxidative catabolism of uracil in prokaryotes | barbiturate + reduced acceptor | - |
? | |
| 3.5.2.1 | barbiturate + H2O | Klebsiella aerogenes | induced by uracil, enzyme is involved in the oxidative catabolism of uracil | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.17.99.4 | Klebsiella aerogenes | - |
- |
- |
| 3.5.2.1 | Klebsiella aerogenes | - |
- |
- |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.17.99.4 | 0.0115 | - |
- |
Klebsiella aerogenes |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.17.99.4 | uracil + acceptor | barbiturate, isobarbiturate, 5-methylbarbiturate, 6-methyluracil, dihydrothymine, dihydrouracil, 2-thiouracil, 2-thiothymine, 2-thio-5-methyluracil and cytosine are no substrates | Klebsiella aerogenes | barbiturate + reduced acceptor | - |
? | |
| 1.17.99.4 | uracil + acceptor | reaction in two-step oxidative catabolism of uracil in prokaryotes | Klebsiella aerogenes | barbiturate + reduced acceptor | - |
? | |
| 3.5.2.1 | barbiturate + 2 H2O | - |
Klebsiella aerogenes | malonate + urea | - |
? | |
| 3.5.2.1 | barbiturate + H2O | induced by uracil, enzyme is involved in the oxidative catabolism of uracil | Klebsiella aerogenes | ? | - |
? | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 1.17.99.4 | 30 | - |
assay at | Klebsiella aerogenes |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.17.99.4 | 2,6-dichlorophenolindophenol | required as electron acceptor, promotes barbiturate formation better than methylene blue | Klebsiella aerogenes | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
