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Literature summary extracted from
- Fatty acid hydroxylase of the fungus Fusarium oxysporum is possibly a fused protein of cytochrome P-450 and its reductase (1994), Biochem. Biophys. Res. Commun., 202, 586-590.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.15.3 | Emulgen 913 | needs detergent 0.1% | Fusarium oxysporum |  |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.15.3 | 8-hydroxyquinoline | no inhibition | Fusarium oxysporum | |
| 1.14.15.3 | CO | - |
Fusarium oxysporum | |
| 1.14.15.3 | diethyldithiocarbamate | reduces activity to 88% | Fusarium oxysporum | |
| 1.14.15.3 | KCN | - |
Fusarium oxysporum | |
| 1.14.15.3 | menadione | - |
Fusarium oxysporum | |
| 1.14.15.3 | additional information | no inhibition by metyrapone | Fusarium oxysporum |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.14.15.3 | microsome | - |
Fusarium oxysporum | - |
- |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.15.3 | Fe | addition of hemine enhances activity to 240% | Fusarium oxysporum | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.15.3 | n-alkane + NAD(P)H + H+ + O2 | Fusarium oxysporum | - |
n-alkanol + NAD(P)+ + H2O | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.15.3 | Fusarium oxysporum | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.15.3 | fatty acid + NAD(P)H + H+ + O2 | NADPH-P-450 reductase and omega-hydrolase are 1 protein | Fusarium oxysporum | omega-hydroxy fatty acid + NAD(P)+ + H2O | - |
? | |
| 1.14.15.3 | lauric acid + NAD(P)H + H+ + O2 | - |
Fusarium oxysporum | 12-hydroxydodecanoic acid + NAD(P)+ + H2O | - |
? | |
| 1.14.15.3 | n-alkane + NAD(P)H + H+ + O2 | - |
Fusarium oxysporum | n-alkanol + NAD(P)+ + H2O | - |
? | |
| 1.14.15.3 | palmitic acid + NAD(P)H + H+ + O2 | - |
Fusarium oxysporum | 16-hydroxyhexadecanoic acid + NAD(P)+ + H2O | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.14.15.3 | 7 | - |
- |
Fusarium oxysporum |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.15.3 | FAD | - |
Fusarium oxysporum | |
| 1.14.15.3 | FMN | - |
Fusarium oxysporum | |
| 1.14.15.3 | NADPH | - |
Fusarium oxysporum | |
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