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Literature summary extracted from
- Studies on the nature of steroid 11-beta hydroxylation (1957), Biochim. Biophys. Acta, 23, 655-656.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.14.15.4 | mitochondrion | - |
Bos taurus | 5739 | - |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.15.4 | Bos taurus | - |
calf | - |
| 1.14.15.4 | Oryctolagus cuniculus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.14.15.4 | adrenal gland | - |
Bos taurus | - |
| 1.14.15.4 | liver | - |
Bos taurus | - |
| 1.14.15.4 | liver | - |
Oryctolagus cuniculus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.15.4 | 4-pregnen-21-ol-3,20-dione + reduced adrenal ferredoxin + O2 | 11-hydroxylation | Bos taurus | 4-pregnene-11,21-diol-3,20-dione + oxidized adrenal ferredoxin + H2O | - |
? |  |
| 1.14.15.4 | 4-pregnen-21-ol-3,20-dione + reduced adrenal ferredoxin + O2 | 11-hydroxylation | Oryctolagus cuniculus | 4-pregnene-11,21-diol-3,20-dione + oxidized adrenal ferredoxin + H2O | - |
? | |
| 1.14.15.4 | 4-pregnene-17,21-diol-3,20-dione + reduced adrenal ferredoxin + O2 | 11-hydroxylation | Bos taurus | 4-pregnene-11,17,21-triol-3,20-dione + oxidized adrenal ferredoxin + H2O | - |
? | |
| 1.14.15.4 | 4-pregnene-17,21-diol-3,20-dione + reduced adrenal ferredoxin + O2 | 11-hydroxylation | Oryctolagus cuniculus | 4-pregnene-11,17,21-triol-3,20-dione + oxidized adrenal ferredoxin + H2O | - |
? | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 1.14.15.4 | 37 | - |
assay at | Bos taurus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.14.15.4 | 7.4 | - |
assay at | Bos taurus |
pH Range
| EC Number | pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.14.15.4 | 7 | 7.2 | - |
Bos taurus |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.15.4 | NADPH | - |
Bos taurus | |
| 1.14.15.4 | NADPH | - |
Oryctolagus cuniculus | |
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Release 2023.1 (January 2023)
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