EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.172 | NADH | uncompetitive inhibition at high concentrations | Homo sapiens | |
1.1.1.172 | oxalate | 10% inhibition at 0.5 mM | Homo sapiens | |
1.1.1.172 | p-chloromercuribenzoate | slight inhibition at 0.02 mM, combined with 0.26 mM SDS | Homo sapiens | |
1.1.1.172 | SDS | slight inhibition at 0.26 mM, combined with 0.02 mM p-chloromercuribenzoate | Homo sapiens |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.1.1.172 | 0.011 | - |
NADH | - |
Homo sapiens | |
1.1.1.172 | 2.6 | - |
2-oxoadipate | - |
Homo sapiens |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.1.1.172 | 95000 | - |
gel filtration | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.172 | 2-oxoadipate + NADH | Homo sapiens | highly specific | 2-hydroxyadipate + NAD+ | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.172 | Homo sapiens | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.1.1.172 | near homogeneity, chromatography techniques, electrofocusing | Homo sapiens |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.1.1.172 | placenta | - |
Homo sapiens | - |
EC Number | Storage Stability | Organism |
---|---|---|
1.1.1.172 | 4°C, 25 mM potassium phosphate, pH 7.5, 20% glycerol, no decrease of activity for several months | Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.172 | 2-oxoadipate + NADH | highly specific | Homo sapiens | 2-hydroxyadipate + NAD+ | - |
? |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.172 | NADH | - |
Homo sapiens |