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Literature summary extracted from

  • Daly, A.K.; Mantle, T.J.
    The kinetic mechanism of the major form of ox kidney aldehyde reductase with D-glucuronic acid (1982), Biochem. J., 205, 381-388.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.2 benzoic acid
-
 Bos taurus
1.1.1.2 L-Gulonic acid product inhibition Bos taurus
1.1.1.2 NADP+ product inhibition Bos taurus
1.1.1.2 NADPH product inhibition Bos taurus
1.1.1.2 NADPH
-
 Sus scrofa
1.1.1.2 sodium valproate
-
 Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.2 D-glucuronate + NADPH Sus scrofa
-
 L-gulonate + NADP+
-
 ?
1.1.1.2 D-glucuronate + NADPH Bos taurus
-
 L-gulonate + NADP+
-
 ?
1.1.1.2 D-glyceraldehyde + NADPH + H+ Sus scrofa
-
 glycerol + NADP+
-
 r
1.1.1.2 L-glyceraldehyde + NADPH Sus scrofa
-
 glycerol + NADP+
-
 r
1.1.1.2 L-gulonic acid + NADP+ Sus scrofa
-
 D-glucuronic acid + NADPH
-
 ?
1.1.1.2 L-gulonic acid + NADP+ Bos taurus
-
 D-glucuronic acid + NADPH
-
 ?
1.1.1.2 succinic semialdehyde + NADPH + H+ Sus scrofa
-
 4-hydroxybutyrate + NADP+
-
 r
1.1.1.2 succinic semialdehyde + NADPH + H+ Bos taurus
-
 4-hydroxybutyrate + NADP+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.2 Bos taurus
-
 ox
-
1.1.1.2 Saccharomyces cerevisiae
-
 yeast
-
1.1.1.2 Sus scrofa
-
 pig
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.2 kidney
-
 Sus scrofa
-
1.1.1.2 kidney
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.2 3-pyridinecarboxaldehyde + NADPH
-
 Sus scrofa 3-pyridinemethanol + NADP+
-
 r
1.1.1.2 3-pyridinecarboxaldehyde + NADPH
-
 Bos taurus 3-pyridinemethanol + NADP+
-
 ?
1.1.1.2 D-glucuronate + NADPH
-
 Sus scrofa L-gulonate + NADP+
-
 ?
1.1.1.2 D-glucuronate + NADPH
-
 Bos taurus L-gulonate + NADP+
-
 ?
1.1.1.2 D-glyceraldehyde + NADPH + H+
-
 Sus scrofa glycerol + NADP+
-
 r
1.1.1.2 L-glyceraldehyde + NADPH
-
 Sus scrofa glycerol + NADP+
-
 r
1.1.1.2 L-gulonic acid + NADP+
-
 Sus scrofa D-glucuronic acid + NADPH
-
 ?
1.1.1.2 L-gulonic acid + NADP+
-
 Bos taurus D-glucuronic acid + NADPH
-
 ?
1.1.1.2 L-gulonic acid + NADPH
-
 Sus scrofa D-glucuronic acid + NADP+
-
 ?
1.1.1.2 L-gulonic acid + NADPH
-
 Bos taurus D-glucuronic acid + NADP+
-
 ?
1.1.1.2 p-nitrobenzaldehyde + NADPH
-
 Sus scrofa p-nitrobenzylalcohol + NADP+
-
 r
1.1.1.2 p-nitrobenzaldehyde + NADPH
-
 Bos taurus p-nitrobenzylalcohol + NADP+
-
 r
1.1.1.2 succinic semialdehyde + NADPH + H+
-
 Sus scrofa 4-hydroxybutyrate + NADP+
-
 r
1.1.1.2 succinic semialdehyde + NADPH + H+
-
 Bos taurus 4-hydroxybutyrate + NADP+
-
 r

Synonyms

EC Number Synonyms Comment Organism
1.1.1.2 yeast alcohol dehydrogenase
-
 Saccharomyces cerevisiae