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Literature summary extracted from

  • Adam, Pascal; Duncan, T.M.; McIntyre, J.O.; Carter, C.E.; Fu, C.; Melin, M.; Latruffe, N.; Fleischer, S.
    Monoclonal antibodies for structure-function studies of (R)-3-hydroxybutyrate dehydrogenase, a lipid-dependent membrane-bound enzyme (1993), Biochem. J., 292, 863-872.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.1.1.30 phosphatidylcholine
-
 Rattus norvegicus
1.1.1.30 phosphatidylcholine
-
 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.1.30 cytoplasm
-
 Bos taurus 5737
-
1.1.1.30 mitochondrion
-
 Rattus norvegicus 5739
-
1.1.1.30 mitochondrion
-
 Bos taurus 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.30 (R)-3-hydroxybutanoate + NAD+ Rattus norvegicus
-
 acetoacetate + NADH
-
 r
1.1.1.30 (R)-3-hydroxybutanoate + NAD+ Bos taurus
-
 acetoacetate + NADH
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.30 Bos taurus
-
-
-
1.1.1.30 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.30 heart
-
 Rattus norvegicus
-
1.1.1.30 heart
-
 Bos taurus
-
1.1.1.30 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.30 0.54
-
 submitochondrial vesicles Bos taurus
1.1.1.30 2.7
-
 submitochondrial vesicles Rattus norvegicus
1.1.1.30 41
-
 purified enzyme, reconstituted with mitochondrial phospholipids Rattus norvegicus
1.1.1.30 86
-
 purified enzyme, reconstituted with mitochondrial phospholipids Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.30 (R)-3-hydroxybutanoate + NAD+
-
 Rattus norvegicus acetoacetate + NADH
-
 r
1.1.1.30 (R)-3-hydroxybutanoate + NAD+
-
 Bos taurus acetoacetate + NADH
-
 r

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.30 NAD+
-
 Rattus norvegicus
1.1.1.30 NAD+
-
 Bos taurus