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Literature summary extracted from

  • Cortese, J.D.; Fleischer, S.
    Noncooperative vs. cooperative reactivation of D-beta-hydroxybutyrate dehydrogenase: multiple equilibria for lecithin binding are determined by the physical state (soluble vs. bilayer) and composition of the phospholipids (1987), Biochemistry, 26, 5283-5293.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.1.1.30 phosphatidylcholine state of phosphatidylcholine determines nature of activation, noncooperative for soluble phosphatidylcholine, cooperative for bilayer phosphatidylcholine Rattus norvegicus
1.1.1.30 phosphatidylcholine state of phosphatidylcholine determines nature of activation, noncooperative for soluble phosphatidylcholine, cooperative for bilayer phosphatidylcholine Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.1.30 mitochondrion
-
 Rattus norvegicus 5739
-
1.1.1.30 mitochondrion
-
 Bos taurus 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.30 (R)-3-hydroxybutanoate + NAD+ Rattus norvegicus
-
 acetoacetate + NADH
-
 r
1.1.1.30 (R)-3-hydroxybutanoate + NAD+ Bos taurus
-
 acetoacetate + NADH
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.30 Bos taurus
-
-
-
1.1.1.30 Rattus norvegicus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.30 (R)-3-hydroxybutanoate + NAD+
-
 Rattus norvegicus acetoacetate + NADH
-
 r
1.1.1.30 (R)-3-hydroxybutanoate + NAD+
-
 Bos taurus acetoacetate + NADH
-
 r

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.30 NAD+
-
 Rattus norvegicus
1.1.1.30 NAD+
-
 Bos taurus