Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • McIntosh, C.A.
    Partial purification and characteristics of membrane-associated NAD+-dependent isocitrate dehydrogenase activity from etiolated pea mitochondria (1997), Plant Sci., 129, 9-20.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.41 NADH competitive inhibitor Pisum sativum

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.41 0.33
-
 NAD+ membrane-associated ICDH Pisum sativum

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.1.41 mitochondrion
-
 Pisum sativum 5739
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.1.1.41 Mg2+
-
 Pisum sativum
1.1.1.41 Mn2+ requires divalent cations Pisum sativum

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.41 320000
-
 gel filtration Pisum sativum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.41 isocitrate + NAD+ Pisum sativum
-
 2-oxoglutarate + CO2 + NADH + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.41 Pisum sativum
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.41
-
 Pisum sativum

Storage Stability

EC Number Storage Stability Organism
1.1.1.41 4°C, glycerol 20%, 35-40% of original activity after 96 h, membrane-associated ICDH Pisum sativum

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.41 isocitrate + NAD+
-
 Pisum sativum 2-oxoglutarate + CO2 + NADH + H+
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.41 7.5
-
-
 Pisum sativum

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.41 NAD+
-
 Pisum sativum