Literature summary extracted from

Macfarlane, N.; Reynolds, H.; Matthews, B.; Dalziel, K.
Purification and molecular properties of NADP-linked isocitrate dehydrogenase from ox heart mitochondria (1977), Biochem. Soc. Trans., 5, 790-793.

Crystallization (Commentary)

EC Number	Crystallization (Comment)	Organism
1.1.1.42	-	Bos taurus

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
1.1.1.42	cytosol	-	Bos taurus	5829	-
1.1.1.42	mitochondrion	-	Bos taurus	5739	-

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
1.1.1.42	45000	-	alpha2, 2 * 45000, SDS-PAGE	Bos taurus
1.1.1.42	90000	-	gel filtration, ultracentrifugation, PAGE	Bos taurus

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.1.1.42	isocitrate + NADP+	Bos taurus	-	2-oxoglutarate + NADPH + H+ + CO2	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.1.1.42	Bos taurus	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
1.1.1.42	-	Bos taurus

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.1.1.42	heart	-	Bos taurus	-
1.1.1.42	liver	-	Bos taurus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.1.1.42	isocitrate + NADP+	-	Bos taurus	2-oxoglutarate + NADPH + H+ + CO2	-	?

Subunits

EC Number	Subunits	Comment	Organism
1.1.1.42	dimer	alpha2, 2 * 45000, SDS-PAGE	Bos taurus

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.1.1.42	NADPH	-	Bos taurus

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Release 2023.1 (January 2023)