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Literature summary extracted from
- Purification and properties of cytosolic NADP-isocitrate dehydrogenase from Chlamydomonas reinhardtii (1996), Plant Physiol. Biochem., 34, 673-676.
No PubMed abstract available
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.42 | 2,3-Butanedione | - |
Chlamydomonas reinhardtii |  |
| 1.1.1.42 | Phenylglyoxal | - |
Chlamydomonas reinhardtii | |
| 1.1.1.42 | pyridoxal 5'-phosphate | - |
Chlamydomonas reinhardtii | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.1.1.42 | cytosol | - |
Chlamydomonas reinhardtii | 5829 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.42 | Mn2+ | - |
Chlamydomonas reinhardtii | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.42 | 40000 | - |
alpha2, 2 * 40000, SDS-PAGE | Chlamydomonas reinhardtii |
| 1.1.1.42 | 70000 | - |
gel filtration | Chlamydomonas reinhardtii |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.42 | isocitrate + NADP+ | Chlamydomonas reinhardtii | - |
2-oxoglutarate + NADPH + H+ + CO2 | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.1.1.42 | Chlamydomonas reinhardtii | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.1.1.42 | - |
Chlamydomonas reinhardtii |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.42 | isocitrate + NADP+ | - |
Chlamydomonas reinhardtii | 2-oxoglutarate + NADPH + H+ + CO2 | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.1.1.42 | dimer | alpha2, 2 * 40000, SDS-PAGE | Chlamydomonas reinhardtii |
Temperature Stability [°C]
| EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.42 | 45 | - |
after 10 min completely inactivated in absence of substrate | Chlamydomonas reinhardtii |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.42 | NADP+ | - |
Chlamydomonas reinhardtii | |
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