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Literature summary extracted from

  • Al-Quadan, F.; Wender, S.H.; Smith, E.C.
    The effect of some phenolic compounds on the activity of 6-phosphogluconate dehydrogenase from tobacco tissue cultures (1981), Phytochemistry, 20, 961-964.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.1.1.44 2,3-diphosphoglycerate activates both isoenzymes up to 200% of their original activity Nicotiana tabacum

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.44 6-methoxy-7-hydroxycoumarin scopolin Nicotiana tabacum
1.1.1.44 caffeic acid
-
 Nicotiana tabacum
1.1.1.44 chlorogenic acid
-
 Nicotiana tabacum
1.1.1.44 D-Glucose 1,6-bisphosphate
-
 Nicotiana tabacum
1.1.1.44 esculetin
-
 Nicotiana tabacum
1.1.1.44 esculin
-
 Nicotiana tabacum
1.1.1.44 ferulic acid
-
 Nicotiana tabacum
1.1.1.44 p-coumaric acid
-
 Nicotiana tabacum
1.1.1.44 scopoletin
-
 Nicotiana tabacum

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.44 69000 72000 2 isoenzymes, gel filtration Nicotiana tabacum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.44 6-phospho-D-gluconate + NADP+ Nicotiana tabacum enzyme specific for the oxidative pentose phosphate pathway D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
1.1.1.44 6-phospho-D-gluconate + NADP+ Nicotiana tabacum W-38 enzyme specific for the oxidative pentose phosphate pathway D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.44 Nicotiana tabacum
-
 W-38
-
1.1.1.44 Nicotiana tabacum W-38
-
 W-38
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.44
-
 Nicotiana tabacum

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.44 leaf
-
 Nicotiana tabacum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.44 6-phospho-D-gluconate + NADP+
-
 Nicotiana tabacum D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
1.1.1.44 6-phospho-D-gluconate + NADP+ enzyme specific for the oxidative pentose phosphate pathway Nicotiana tabacum D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
1.1.1.44 6-phospho-D-gluconate + NADP+
-
 Nicotiana tabacum W-38 D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
1.1.1.44 6-phospho-D-gluconate + NADP+ enzyme specific for the oxidative pentose phosphate pathway Nicotiana tabacum W-38 D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r