Any feedback?
Literature summary extracted from
- Inhibition of 3-phosphoglycerate dehydrogenase from Pisum sativum by purine nucleotides (1973), Biochem. J., 135, 563-565.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.95 | ADP | free ADP is more effective than the magnesium complex | Pisum sativum |  |
| 1.1.1.95 | ATP | free ATP is more effective than the magnesium complex | Pisum sativum | |
| 1.1.1.95 | GDP | - |
Pisum sativum | |
| 1.1.1.95 | GTP | - |
Pisum sativum | |
| 1.1.1.95 | L-serine | - |
Pisum sativum | |
| 1.1.1.95 | p-hydroxymercuribenzoate | - |
Pisum sativum | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.1.1.95 | additional information | - |
additional information | - |
Pisum sativum | |
| 1.1.1.95 | 0.00013 | - |
3-phosphohydroxypyruvate | 25°C | Pisum sativum | |
| 1.1.1.95 | 0.00016 | - |
3-acetylpyridine-NADH | 25°C | Pisum sativum | |
| 1.1.1.95 | 0.00025 | - |
3-acetylpyridine-NAD+ | 25°C | Pisum sativum | |
| 1.1.1.95 | 0.0005 | - |
NADH | 25°C | Pisum sativum | |
| 1.1.1.95 | 0.0054 | - |
3-acetylpyridine-NAD+ | 37°C | Pisum sativum | |
| 1.1.1.95 | 0.0078 | - |
NAD+ | - |
Pisum sativum | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.95 | MgCl2 | no effect on enzyme activity, but hinders enzyme inhibition by ATP and ADP | Pisum sativum | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.1.1.95 | Pisum sativum | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.1.1.95 | epicotyl | etiolated | Pisum sativum | - |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 1.1.1.95 | 5°C, 60% loss of activity, 24 h | Pisum sativum |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.95 | 3-phosphoglycerate + NAD+ | - |
Pisum sativum | 3-phosphohydroxypyruvate + NADH | - |
r | |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.95 | 3-acetylpyridine-NAD+ | - |
Pisum sativum | |
| 1.1.1.95 | 3-acetylpyridine-NADH | - |
Pisum sativum | |
| 1.1.1.95 | deamino-NAD+ | - |
Pisum sativum | |
| 1.1.1.95 | NAD+ | - |
Pisum sativum | |
| 1.1.1.95 | NADH | - |
Pisum sativum | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
