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Literature summary extracted from

  • Sims, K.L.; Davis, G.A.
    Subcellular distribution of succinate-semialdehyde dehydrogenase in rat brain (1973), Eur. J. Biochem., 35, 450-453.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.1.16 5,5-dipropylpentanoate
-
 Rattus norvegicus
1.2.1.16 dipropylacetate
-
 Rattus norvegicus
1.2.1.16 p-Hydroxybenzaldehyde
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.2.1.16 mitochondrion
-
 Rattus norvegicus 5739
-
1.2.1.16 synaptosome
-
 Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.16 succinate semialdehyde + NADP+ + H2O Rattus norvegicus involved in the degradation of gamma-aminobutyrate succinate + NADPH + H+
-
 ?
1.2.1.16 succinate semialdehyde + NADP+ + H2O Rattus norvegicus Sprague-Dawley involved in the degradation of gamma-aminobutyrate succinate + NADPH + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.16 Rattus norvegicus
-
 Sprague-Dawley strain
-
1.2.1.16 Rattus norvegicus Sprague-Dawley
-
 Sprague-Dawley strain
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.1.16 brain
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.16 succinate semialdehyde + NADP+ + H2O
-
 Rattus norvegicus succinate + NADPH + H+
-
 ?
1.2.1.16 succinate semialdehyde + NADP+ + H2O involved in the degradation of gamma-aminobutyrate Rattus norvegicus succinate + NADPH + H+
-
 ?
1.2.1.16 succinate semialdehyde + NADP+ + H2O
-
 Rattus norvegicus Sprague-Dawley succinate + NADPH + H+
-
 ?
1.2.1.16 succinate semialdehyde + NADP+ + H2O involved in the degradation of gamma-aminobutyrate Rattus norvegicus Sprague-Dawley succinate + NADPH + H+
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
1.2.1.16
-
 2 substancial progressive loss of activity, sucrose fractions Rattus norvegicus
1.2.1.16 25
-
 substancial progressive loss of activity, sucrose fractions Rattus norvegicus