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Literature summary extracted from

  • Walsh, J.M.; Clark, J.B.
    Studies on the control of 4-aminobutyrate metabolism in synaptosomal and free rat brain mitochondria (1976), Biochem. J., 160, 147-157.
    View publication on PubMedView publication on EuropePMC

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.2.1.16 1.4
-
 succinate semialdehyde synaptosomes Rattus norvegicus
1.2.1.16 1.5
-
 succinate semialdehyde mitochondria of non-synaptic origin Rattus norvegicus
1.2.1.16 9.4
-
 NAD+ mitochondria of non-synaptic origin Rattus norvegicus
1.2.1.16 17
-
 NAD+ synaptosomes Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.2.1.16 mitochondrion of non-synaptic origin Rattus norvegicus 5739
-
1.2.1.16 synaptosome
-
 Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.16 Rattus norvegicus
-
 Wistar strain
-
1.2.1.16 Rattus norvegicus Wistar
-
 Wistar strain
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.2.1.16 chromatography on Celite 535 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.1.16 brain
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.16 succinate semialdehyde + NAD+ + H2O
-
 Rattus norvegicus succinate + NADH + H+
-
 r
1.2.1.16 succinate semialdehyde + NAD+ + H2O
-
 Rattus norvegicus Wistar succinate + NADH + H+
-
 r
1.2.1.16 succinate semialdehyde + NADP+ + H2O
-
 Rattus norvegicus succinate + NADPH + H+
-
 ?
1.2.1.16 succinate semialdehyde + NADP+ + H2O
-
 Rattus norvegicus Wistar succinate + NADPH + H+
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.16 NAD+
-
 Rattus norvegicus