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Literature summary extracted from

  • Satya Narayan, V.; Madhusudanan Nair, P.
    Potato tuber succinate semialdehyde dehydrogenase: purification and characterization (1989), Arch. Biochem. Biophys., 275, 469-477.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.2.1.24 2-mercaptoethanol activates Solanum tuberosum
1.2.1.24 dithiothreitol activates Solanum tuberosum
1.2.1.24 glutathione activates Solanum tuberosum
1.2.1.24 L-Cys activates Solanum tuberosum

General Stability

EC Number General Stability Organism
1.2.1.24 freezing in absence of glycerol results in inactivation Solanum tuberosum

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.1.24 4-hydroxybenzaldehyde
-
 Solanum tuberosum
1.2.1.24 acetaldehyde 1 mM, 40% inhibition Solanum tuberosum
1.2.1.24 AMP 1 mM, 17% inhibition Solanum tuberosum
1.2.1.24 arsenite
-
 Solanum tuberosum
1.2.1.24 Cd2+
-
 Solanum tuberosum
1.2.1.24 Cu2+
-
 Solanum tuberosum
1.2.1.24 Dithionitrobenzoate
-
 Solanum tuberosum
1.2.1.24 glyoxylate 1 mM, 33% inhibition Solanum tuberosum
1.2.1.24 Hg2+
-
 Solanum tuberosum
1.2.1.24 NADH
-
 Solanum tuberosum
1.2.1.24 NEM
-
 Solanum tuberosum
1.2.1.24 p-hydroxymercuribenzoate
-
 Solanum tuberosum
1.2.1.24 Zn2+
-
 Solanum tuberosum

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.2.1.24 0.0046
-
 succinate semialdehyde
-
 Solanum tuberosum
1.2.1.24 0.031
-
 NAD+
-
 Solanum tuberosum

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.2.1.24 35000
-
 4 * 35000, SDS-PAGE Solanum tuberosum
1.2.1.24 145000
-
 gel filtration Solanum tuberosum

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.24 Solanum tuberosum
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.2.1.24
-
 Solanum tuberosum

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.2.1.24 6.49
-
-
 Solanum tuberosum

Storage Stability

EC Number Storage Stability Organism
1.2.1.24 -20°C, 20 mM sodium diphosphate buffer, pH 7.2, 14 mM 2-mercaptoethanol, 25% v/v glycerol, 2-3 months, retains 80-85% of the activity Solanum tuberosum
1.2.1.24 0-2°C, 24 h, 50% loss of activity Solanum tuberosum

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.24 succinate semialdehyde + NAD+ + H2O
-
 Solanum tuberosum succinate + NADH
-
 ?

Subunits

EC Number Subunits Comment Organism
1.2.1.24 tetramer 4 * 35000, SDS-PAGE Solanum tuberosum

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.2.1.24 9
-
-
 Solanum tuberosum

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.24 NAD+
-
 Solanum tuberosum