EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.69 | Benzamidine hydrochloride | - |
Bos taurus | |
3.4.21.69 | Benzamidine hydrochloride | - |
Homo sapiens | |
3.4.21.69 | diisopropyl fluorophosphate | - |
Bos taurus | |
3.4.21.69 | diisopropyl fluorophosphate | - |
Homo sapiens | |
3.4.21.69 | phenylmethylsulfonyl fluoride | - |
Bos taurus | |
3.4.21.69 | phenylmethylsulfonyl fluoride | - |
Homo sapiens |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.4.21.69 | 21000 | - |
1 * 41000 + 1 * 21000, bovine protein C, SDS-PAGE of reduced protein, heavy and light chain are connected by a disulfide bond, cleavage of Arg12-Leu13 in the heavy chain releases a small activation peptide, MW 1400 and protein Ca | Bos taurus |
3.4.21.69 | 41000 | - |
1 * 41000 + 1 * 21000, bovine protein C, SDS-PAGE of reduced protein, heavy and light chain are connected by a disulfide bond, cleavage of Arg12-Leu13 in the heavy chain releases a small activation peptide, MW 1400 and protein Ca | Bos taurus |
3.4.21.69 | 54300 | - |
bovine, protein C, amino acid and carbohydrate composition data, conversion to protein Ca by hydrolysis of a specific peptide bond in the amino-terminal region of the heavy chain between Arg14 and Ile15, giving rise to protein Ca, MW 52650 and an activation peptide, MW 1650 | Bos taurus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.21.69 | Bos taurus | - |
- |
- |
3.4.21.69 | Homo sapiens | - |
- |
- |
EC Number | Posttranslational Modification | Comment | Organism |
---|---|---|---|
3.4.21.69 | glycoprotein | bovine protein C contains 14% carbohydrate, approximately 15 residues of hexose, 12 residues of hexosamine and 9 residues of sialic acid distributed in 3 carbohydrate chains, human protein C contains 23% carbohydrate, approximately 14 residues of galactose, 21 residues of mannose, 23 residues of glucosamine and 12 residues of sialic acid | Homo sapiens |
3.4.21.69 | glycoprotein | bovine protein C contains 14% carbohydrate, approximately 15 residues of hexose, 12 residues of hexosamine and 9 residues of sialic acid distributed in 3 carbohydrate chains, human protein C contains 23% carbohydrate, approximately 14 residues of galactose, 21 residues of mannose, 23 residues of glucosamine and 12 residues of sialic acid | Bos taurus |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.4.21.69 | - |
Homo sapiens |
3.4.21.69 | - |
Bos taurus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.21.69 | plasma | - |
Homo sapiens | - |
3.4.21.69 | plasma | - |
Bos taurus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.69 | Factor Va + H2O | - |
Homo sapiens | ? | - |
? | |
3.4.21.69 | Factor Va + H2O | - |
Bos taurus | ? | - |
? | |
3.4.21.69 | Factor VIIIa + H2O | - |
Homo sapiens | ? | - |
? | |
3.4.21.69 | Factor VIIIa + H2O | - |
Bos taurus | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.4.21.69 | dimer | 1 * 41000 + 1 * 21000, bovine protein C, SDS-PAGE of reduced protein, heavy and light chain are connected by a disulfide bond, cleavage of Arg12-Leu13 in the heavy chain releases a small activation peptide, MW 1400 and protein Ca | Bos taurus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.69 | vitamin K | enzyme is dependent on | Homo sapiens | |
3.4.21.69 | vitamin K | enzyme is dependent on | Bos taurus |