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Literature summary extracted from
- (R)-lactyl-CoA dehydratase from Clostridium propionicum. Stereochemistry of the dehydration of (R)-2-hydroxybutyryl-CoA to crotonyl-CoA (1992), Eur. J. Biochem., 206, 547-552.
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.1.54 | lactoyl-CoA + H2O | Anaerotignum propionicum | - |
? | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.2.1.54 | Anaerotignum propionicum | - |
- |
- |
Reaction
| EC Number | Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|---|
| 4.2.1.54 | (R)-lactoyl-CoA = acryloyl-CoA + H2O | 3Si hydrogen is removed, no radical mechanism | Anaerotignum propionicum |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 4.2.1.54 | additional information | - |
strict anaerobic conditions | Anaerotignum propionicum |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.1.54 | (2R)-2-hydroxybutyryl-CoA | stereospecific elimination of the 3Si hydrogen | Anaerotignum propionicum | crotonyl-CoA + H2O | - |
? | |
| 4.2.1.54 | lactoyl-CoA + H2O | - |
Anaerotignum propionicum | ? | - |
? | |
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Release 2023.1 (January 2023)
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