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Literature summary extracted from

  • Nishinaka, T.; Kinoshita, Y.; Terada, N.; Terada, T.; Mizoguchi, T.; Nishihara, T.
    Characterization of multiple forms of carbonyl reductase from chicken liver (1993), Enzyme, 46, 221-228.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.184 Barbital
-
Gallus gallus
1.1.1.184 coumarin
-
Gallus gallus
1.1.1.184 CuCl2 only enzyme forms CR2, CR3 Gallus gallus
1.1.1.184 quercitrin
-
Gallus gallus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.184 24000
-
2 * 24000, SDS-PAGE, enzyme form CR1 Gallus gallus
1.1.1.184 32000
-
gel filtration, enzyme forms CR2, CR3 Gallus gallus
1.1.1.184 48000
-
gel filtration, enzyme form CR1 Gallus gallus

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.184 Gallus gallus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.184 3 forms from liver: CR1, CR2, CR3 Gallus gallus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.184 liver
-
Gallus gallus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.184 4-benzoylpyridine + NADPH
-
Gallus gallus ?
-
?
1.1.1.184 4-nitrobenzaldehyde + NADPH
-
Gallus gallus 4-nitrobenzyl alcohol + NADP+
-
?
1.1.1.184 5alpha-androstane-3,17-dione + NADPH
-
Gallus gallus ?
-
?
1.1.1.184 5alpha-dihydrotestosterone + NADPH only enzyme form CR1 Gallus gallus ?
-
?
1.1.1.184 5beta-androstane-3,17-dione + NADPH only enzyme form CR1 Gallus gallus ?
-
?
1.1.1.184 5beta-dihydrotestosterone + NADPH only enzyme form CR1 Gallus gallus ?
-
?
1.1.1.184 9,10-phenanthrenequinone + NADPH
-
Gallus gallus ?
-
?
1.1.1.184 cyclohexanone + NADPH
-
Gallus gallus cyclohexanol + NADP+
-
?
1.1.1.184 menadione + NADPH
-
Gallus gallus ?
-
?
1.1.1.184 additional information NADH only acts as cofactor for enzyme form CR1 Gallus gallus ?
-
?
1.1.1.184 pyridine-3-aldehyde + NADPH
-
Gallus gallus ?
-
?

Subunits

EC Number Subunits Comment Organism
1.1.1.184 dimer 2 * 24000, SDS-PAGE, enzyme form CR1 Gallus gallus
1.1.1.184 monomer SDS-PAGE, enzyme forms CR2, CR3 Gallus gallus