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Literature summary extracted from
- Effect of heme oxygenase inhibitors on soluble guanylyl cyclase activity (1998), Arch. Biochem. Biophys., 359, 8-16.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.6.1.2 | CO | activation | Bos taurus |  |
| 4.6.1.2 | NO | activation | Bos taurus | |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.6.1.2 | zinc (II) protophorphyrin IX | at higher concentrations, 2.5 µM | Bos taurus | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 4.6.1.2 | soluble | - |
Bos taurus | - |
- |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.6.1.2 | Bos taurus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 4.6.1.2 | - |
Bos taurus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 4.6.1.2 | lung | - |
Bos taurus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 4.6.1.2 | 0.11 | - |
- |
Bos taurus |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.6.1.2 | tin(IV) protophorphyrin IX (2+) | activation | Bos taurus | |
| 4.6.1.2 | zinc (II) protophorphyrin IX | activation at nM concentrations | Bos taurus | |
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Release 2023.1 (January 2023)
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