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Literature summary extracted from

  • MacGregor, R.R.; Hamilton, J.W.; Shofstall, R.E.; Cohn, D.V.
    Isolation and characterization of porcine parathyroid cathepsin B (1979), J. Biol. Chem., 254, 4423-4427.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.22.1 antipain
-
Sus scrofa
3.4.22.1 Hg2+
-
Sus scrofa
3.4.22.1 iodoacetamide
-
Sus scrofa
3.4.22.1 iodoacetic acid
-
Sus scrofa
3.4.22.1 leupeptin
-
Sus scrofa
3.4.22.1 N-ethylmaleimide
-
Sus scrofa
3.4.22.1 Zn2+
-
Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.22.1 0.14
-
benzyloxycarbonyl-Val-Lys-Lys-Arg-4-methoxy-beta-naphthylamide
-
Sus scrofa
3.4.22.1 1.25
-
benzyloxycarbonyl-Ala-Arg-Arg-4-methoxy-beta-naphthylamide
-
Sus scrofa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.22.1 25000
-
gel filtration Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.22.1 Proteins + H2O Sus scrofa turnover of intracellular proteins ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.1 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.22.1
-
Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.22.1 liver
-
Sus scrofa
-
3.4.22.1 parathyroid gland
-
Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.22.1 benzyloxycarbonyl-Ala-Arg-Arg-4-methoxy-beta-naphthylamide + H2O
-
Sus scrofa benzyloxycarbonyl-Ala-Arg-Arg + 4-methoxy-beta-naphthylamine
-
?
3.4.22.1 benzyloxycarbonyl-Val-Lys-Lys-Arg-4-methoxy-beta-naphthylamide + H2O
-
Sus scrofa ? + 4-methoxy-beta-naphthylamine
-
?
3.4.22.1 Proteins + H2O turnover of intracellular proteins Sus scrofa ?
-
?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.4.22.1 68
-
benzyloxycarbonyl-Val-Lys-Lys-Arg-4-methoxy-beta-naphthylamide
-
Sus scrofa
3.4.22.1 87
-
benzyloxycarbonyl-Ala-Arg-Arg-4-methoxy-beta-naphthylamide
-
Sus scrofa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.22.1 6 7
-
Sus scrofa

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
3.4.22.1 4.5 7.5 unstable above and below Sus scrofa