Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Rioli, V.; Kato, A.; Portaro, F.C.V.; Cury, G.K.; te Kaat, K.; Vincent, B.; Checler, F.; Camargo, A.C.M.; Glucksman, M.J.; Roberts, J.L.; Hirose, S.; Ferro, E.S.
    Neuropeptide specificity and inhibition of recombinant isoforms of the endopeptidase 3.4.24.16 family: comparison with the related recombinant endopeptidase 3.4.24.15 (1998), Biochem. Biophys. Res. Commun., 250, 5-11.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.24.15 overexpression in Escherichia coli Sus scrofa
3.4.24.16 overexpression of enzyme form EP24.16m and EP24.16c in Escherichia coli Sus scrofa

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.16 dithiothreitol
-
 Sus scrofa
3.4.24.16 Pro-Ile
-
 Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.24.16 membrane EP24.16c is the cytosolic/membrane-bound enzyme form Sus scrofa 16020
-
3.4.24.16 mitochondrion EP24.16m is the mitochondrial enzyme form Sus scrofa 5739
-

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.15 Sus scrofa
-
-
-
3.4.24.16 Sus scrofa
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.15 adrenorphin
-
 Sus scrofa peptide fragments
-
 ?
3.4.24.15 Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg + H2O i.e. bradykinin, cleavage site: Phe5-Ser6 Sus scrofa Arg-Pro-Pro-Gly-Phe + Ser-Pro-Phe-Arg
-
 ?
3.4.24.15 pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 + H2O
-
 Sus scrofa pGlu-His-Trp-Ser-Tyr + Gly-Leu-Arg-Pro-Gly-NH2
-
 ?
3.4.24.15 pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu
-
 Sus scrofa pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg + Arg-Pro-Tyr-Ile-Leu
-
 ?
3.4.24.15 Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile + H2O i.e. dynorphin A(1-8) Sus scrofa Tyr-Gly-Gly-Phe-Leu + Arg-Arg-Ile
-
 ?
3.4.24.15 Val-Tyr-Ile-His-Pro-Phe-His-Leu + H2O i.e. angiotensin I Sus scrofa ?
-
 ?
3.4.24.16 Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg + H2O i.e. bradykinin, cleavage site: Phe5-Ser6 Sus scrofa Arg-Pro-Pro-Gly-Phe + Ser-Pro-Phe-Arg
-
 ?
3.4.24.16 Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu + H2O i.e. angiotensin I, cleavage site: Pro7-Phe8 Sus scrofa Asp-Arg-Val-Tyr-Ile-His-Pro + Phe-His-Leu
-
 ?
3.4.24.16 pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu + H2O specific hydrolysis of the Pro10-Tyr11 bond Sus scrofa pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro + Tyr-Ile-Leu
-
 ?
3.4.24.16 Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile + H2O i.e. dynorphin(1-8) Sus scrofa Tyr-Gly-Gly-Phe-Leu + Arg-Arg-Ile
-
 ?
3.4.24.16 Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-(NH2) + H2O i.e. metorphinamide Sus scrofa Tyr-Gly-Gly-Phe-Met + Arg-Arg-Val-(NH2)
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.15 EP24.15
-
 Sus scrofa
3.4.24.16 EP24.16c the cytosolic/membrane bound enzyme form Sus scrofa
3.4.24.16 EP24.16m the mitochondrial enzyme form Sus scrofa