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Literature summary extracted from

  • Vincent, B.; Vincent, J.P.; Checler, F.
    Purification and characterization of human endopeptidase 3.4.24.16. Comparison with the porcine counterpart indicates a unique cleavage site on neurotensin (1996), Brain Res., 709, 51-58.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.16 1,10-phenanthroline
-
 Homo sapiens
3.4.24.16 1,10-phenanthroline
-
 Sus scrofa
3.4.24.16 EDTA
-
 Homo sapiens
3.4.24.16 EDTA
-
 Sus scrofa
3.4.24.16 iodoacetamide 10 mM, 22% inactivation Homo sapiens
3.4.24.16 iodoacetamide 10 mM, 15% inactivation Sus scrofa
3.4.24.16 leupeptin 11% inhibition Homo sapiens
3.4.24.16 leupeptin 1 mM, 22% inhibition Sus scrofa
3.4.24.16 Pro-Ile
-
 Homo sapiens
3.4.24.16 Pro-Ile
-
 Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.16 Homo sapiens
-
-
-
3.4.24.16 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.24.16
-
 Homo sapiens
3.4.24.16
-
 Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.16 brain
-
 Homo sapiens
-
3.4.24.16 brain
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.24.16 0.0198
-
-
 Sus scrofa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.16 Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg + H2O
-
 Homo sapiens Arg-Pro-Pro-Gly-Phe + Ser-Pro-Phe-Arg
-
 ?
3.4.24.16 Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg + H2O
-
 Sus scrofa Arg-Pro-Pro-Gly-Phe + Ser-Pro-Phe-Arg
-
 ?
3.4.24.16 Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu + H2O
-
 Homo sapiens Asp-Arg-Val-Tyr-Ile-His-Pro + Phe-His-Leu
-
 ?
3.4.24.16 Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu + H2O
-
 Sus scrofa Asp-Arg-Val-Tyr-Ile-His-Pro + Phe-His-Leu
-
 ?
3.4.24.16 pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu + H2O specific hydrolysis of the Pro10-Tyr11 bond Homo sapiens pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro + Tyr-Ile-Leu
-
 ?
3.4.24.16 pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu + H2O specific hydrolysis of the Pro10-Tyr11 bond Sus scrofa pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro + Tyr-Ile-Leu
-
 ?
3.4.24.16 Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile + H2O
-
 Homo sapiens Tyr-Gly-Gly-Phe-Leu + Arg-Arg-Ile
-
 ?
3.4.24.16 Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile + H2O
-
 Sus scrofa Tyr-Gly-Gly-Phe-Leu + Arg-Arg-Ile
-
 ?
3.4.24.16 Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg + H2O i.e. dynorphin(1-9) Homo sapiens peptide fragments
-
 ?