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Literature summary extracted from

  • Nygaard, A.P.
    Lactate dehydrogenases of yeast (1963), The Enzymes, 2nd Ed (Boyer, P. D. , Lardy, H. , Myrbäck, K. , eds. ), 7, 557-565.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.2.4 high ionic strength
-
 Saccharomyces cerevisiae

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.2.4 mitochondrion
-
 Saccharomyces cerevisiae 5739
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.1.2.4 Ca2+ inhibitory Saccharomyces cerevisiae
1.1.2.4 ferricyanide can substitute for cytochrome c Saccharomyces cerevisiae
1.1.2.4 Mg2+ inhibitory Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.2.4 (R)-lactate + 2 ferricytochrome c Saccharomyces cerevisiae
-
 pyruvate + ferrocytochrome c
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.2.4 Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.2.4 (R)-lactate + 2 ferricytochrome c
-
 Saccharomyces cerevisiae pyruvate + ferrocytochrome c
-
 ?
1.1.2.4 (R)-lactate + ferricytochrome c
-
 Saccharomyces cerevisiae pyruvate + ferrocytochrome c
-
 ?
1.1.2.4 D-2-hydroxybutyrate + cytochrome c
-
 Saccharomyces cerevisiae 2-oxobutanoate + ferrocytochrome c
-
 ?
1.1.2.4 D-2-hydroxyvalerate + cytochrome c very poor substrate Saccharomyces cerevisiae 2-oxovalerate + ferrocytochrome c
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.2.4 2,6-dichlorophenolindophenol can substitute for cytochrome c Saccharomyces cerevisiae
1.1.2.4 cytochrome c highly specific Saccharomyces cerevisiae
1.1.2.4 FAD
-
 Saccharomyces cerevisiae
1.1.2.4 phenazine methosulfate can substitute for cytochrome c Saccharomyces cerevisiae