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Literature summary extracted from

  • Bhat, P.; Poissant, L.; Lacroix, A.
    Properties of retinal-oxidizing enzyme activity in rat kidney (1988), Biochim. Biophys. Acta, 967, 211-217.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.3.1 2-Aminobenzaldehyde complete inhibition at 5 mM, partially reversed by retinal Rattus sp.
1.2.3.1 4'-(9-acridinylamino)methanesulfonaniside dose-dependent inhibition, no complete inhibition Rattus sp.
1.2.3.1 acetaldehyde 77% inhibition at 5 mM, partially reversed by retinal Rattus sp.
1.2.3.1 hydroxytoluene butylated, 50% inhibition at 1 mM Rattus sp.
1.2.3.1 p-hydroxymercuribenzoate complete inhibition at 3 mM, reversed by DTT Rattus sp.
1.2.3.1 propyl 3,4,5-trihydroxybenzoate 91% inhibition at 3 mM Rattus sp.
1.2.3.1 Quinacrine 76% inhibition at 1 mM, partially reversed by FAD Rattus sp.
1.2.3.1 retinol complete inhibition at 0.5 mM Rattus sp.

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.2.3.1 cytoplasm
-
 Rattus sp. 5737
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.3.1 all-trans-retinal + O2 + H2O Rattus sp.
-
 all-trans-retinoate + H2O2
-
 ?
1.2.3.1 retinal + O2 + H2O Rattus sp. activity is dependent on vitamin A levels of tissues retinoate + H2O2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.2.3.1 Rattus sp.
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.3.1 kidney
-
 Rattus sp.
-

Storage Stability

EC Number Storage Stability Organism
1.2.3.1 -70°C, stable for 6 months Rattus sp.

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.3.1 all-trans-retinal + O2 + H2O
-
 Rattus sp. all-trans-retinoate + H2O2
-
 ?
1.2.3.1 retinal + O2 + H2O activity is dependent on vitamin A levels of tissues Rattus sp. retinoate + H2O2
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.2.3.1 37
-
-
 Rattus sp.

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.2.3.1 7.5
-
-
 Rattus sp.

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.3.1 FAD
-
 Rattus sp.