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Literature summary extracted from
- Anaerobic lactate oxidation to 3 CO2 by Archaeoglobus fulgidus via the carbon monoxide dehydrogenase pathway: demonstration of the acetyl-CoA carbon-carbon cleavage reaction in cell extract (1990), Arch. Microbiol., 153, 215-218.
No PubMed abstract available
General Stability
| EC Number | General Stability | Organism |
|---|---|---|
| 1.2.7.4 | CN- inactivates | Archaeoglobus fulgidus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.2.7.4 | CN- | - |
Archaeoglobus fulgidus |  |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.2.7.4 | 0.35 | - |
CO | - |
Archaeoglobus fulgidus | |
| 1.2.7.4 | 1.4 | - |
methyl viologen | - |
Archaeoglobus fulgidus | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.2.7.4 | CO + H2O + electron acceptor | Archaeoglobus fulgidus | key enzyme in C1-pathway of acetyl-CoA degradation | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.2.7.4 | Archaeoglobus fulgidus | - |
- |
- |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.2.7.4 | 0.001 | 0.002 | CO2/acetyl-CoA exchange in cell extracts at 85°C | Archaeoglobus fulgidus |
| 1.2.7.4 | 5.7 | - |
CO oxidation in cell-extracts at 85°C, electron acceptor methylviologen | Archaeoglobus fulgidus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.2.7.4 | CO + H2O + electron acceptor | key enzyme in C1-pathway of acetyl-CoA degradation | Archaeoglobus fulgidus | ? | - |
? | |
| 1.2.7.4 | CO + H2O + methyl viologen | catalyzes an exchange reaction between CO and the carbonyl group of acetyl-CoA | Archaeoglobus fulgidus | CO2 + reduced methyl viologen | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.2.7.4 | 7 | 9 | - |
Archaeoglobus fulgidus |
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Release 2023.1 (January 2023)
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