EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.3.1.12 | iodoacetamide | modification of only one cysteinyl residue results in the inactivation | Escherichia coli | |
1.3.1.12 | iodoacetamide | - |
Klebsiella aerogenes | |
1.3.1.12 | iodoacetate | - |
Escherichia coli | |
1.3.1.12 | iodoacetate | - |
Klebsiella aerogenes | |
1.3.1.12 | N-bromosuccinimide | - |
Escherichia coli | |
1.3.1.12 | N-ethylmaleimide | - |
Escherichia coli | |
1.3.1.12 | Tetranitromethane | - |
Escherichia coli |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.3.1.12 | 0.35 | 0.37 | prephenate | - |
Escherichia coli | |
1.3.1.12 | 0.35 | 0.37 | prephenate | - |
Klebsiella aerogenes |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.3.1.12 | prephenate + NAD+ | Escherichia coli | biosynthesis of L-tyrosine | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
? | |
1.3.1.12 | prephenate + NAD+ | Klebsiella aerogenes | biosynthesis of L-tyrosine | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.3.1.12 | Escherichia coli | - |
- |
- |
1.3.1.12 | Klebsiella aerogenes | - |
- |
- |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.3.1.12 | additional information | - |
- |
Escherichia coli |
1.3.1.12 | additional information | - |
- |
Klebsiella aerogenes |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.3.1.12 | prephenate + NAD+ | - |
Escherichia coli | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
? | |
1.3.1.12 | prephenate + NAD+ | - |
Klebsiella aerogenes | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
? | |
1.3.1.12 | prephenate + NAD+ | biosynthesis of L-tyrosine | Escherichia coli | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
? | |
1.3.1.12 | prephenate + NAD+ | biosynthesis of L-tyrosine | Klebsiella aerogenes | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.3.1.12 | chorismate mutase-prephenate dehydrogenase bifunctional enzyme | complex with EC 5.4.99.5 | Escherichia coli |
1.3.1.12 | chorismate mutase-prephenate dehydrogenase bifunctional enzyme | complex with EC 5.4.99.5 | Klebsiella aerogenes |