EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.3.8.1 | CN- | activates the enzyme in reaction with ferricytochrome c or ferricyanide as electron acceptors, but not with flavin D or FAd | Sus scrofa |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.3.8.1 | 4-chloromercuribenzoate | 0.1 mM, 40% inhibition | Bos taurus | |
1.3.8.1 | 4-chloromercuribenzoate | inhibition is reversible by glutathione | Sus scrofa | |
1.3.8.1 | Hg2+ | - |
Sus scrofa | |
1.3.8.1 | additional information | no inhibition by CN- | Sus scrofa |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.3.8.1 | copper | 2 mol copper /mol FAD, cupric ion can be removed by dialysis against cyanide, copper is not involved in redox reaction | Bos taurus | |
1.3.8.1 | Cu2+ | 10-12 copper ions per enzyme molecule, enzyme-bound copper. The Cu2+ does not play a role in the primary reduction of the flavin-bound enzyme | Sus scrofa |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.3.8.1 | 120000 | 220000 | gel filtration | Sus scrofa |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.3.8.1 | butanoyl-CoA + oxidized acceptor | Sus scrofa | - |
crotonyl-CoA + reduced acceptor | - |
r |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.3.8.1 | Bos taurus | - |
- |
- |
1.3.8.1 | Sus scrofa | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.3.8.1 | kidney | - |
Sus scrofa | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.3.8.1 | butanoyl-CoA + oxidized acceptor | - |
Sus scrofa | crotonyl-CoA + reduced acceptor | - |
r | |
1.3.8.1 | additional information | no activity with octanoyl-CoA and acetyl-CoA | Sus scrofa | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.3.8.1 | butyryl CoA dehydrogenase | - |
Sus scrofa |
1.3.8.1 | butyryl coenzyme A dehydrogenase | - |
Sus scrofa |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
1.3.8.1 | 25 | 38 | assay at | Sus scrofa |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
1.3.8.1 | 7 | - |
assay at | Sus scrofa |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.3.8.1 | FAD | about 5 or 6 FAD molecules per enzyme molecule | Bos taurus | |
1.3.8.1 | FAD | enzyme-bound, flavin D | Sus scrofa | |
1.3.8.1 | ferricytochrome c | - |
Sus scrofa | |
1.3.8.1 | riboflavin | enzyme-bound | Sus scrofa |