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Literature summary extracted from

  • Lenich, A.C.; Goodman, S.I.
    The purification and characterization of glutaryl-coenzyme A dehydrogenase from porcine and human liver (1986), J. Biol. Chem., 261, 4090-4096.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.8.6 crotonyl-CoA
-
 Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.3.8.6 0.0011 0.0025 electron-transfer flavoprotein
-
 Sus scrofa
1.3.8.6 0.0012 0.01 glutaryl-CoA
-
 Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.3.8.6 mitochondrion
-
 Homo sapiens 5739
-
1.3.8.6 mitochondrion
-
 Sus scrofa 5739
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.3.8.6 47000
-
 4 * 47000, SDS-PAGE Sus scrofa
1.3.8.6 58800
-
 4 * 58800, SDS-PAGE Homo sapiens
1.3.8.6 190500
-
 gel filtration Sus scrofa
1.3.8.6 256000
-
 gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.3.8.6 Homo sapiens
-
-
-
1.3.8.6 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.3.8.6
-
 Homo sapiens
1.3.8.6
-
 Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.8.6 liver
-
 Homo sapiens
-
1.3.8.6 liver
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.3.8.6 2.3
-
-
 Sus scrofa
1.3.8.6 7.4
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.8.6 butyryl-CoA + acceptor
-
 Sus scrofa ? + reduced acceptor
-
 ?
1.3.8.6 glutaryl-CoA + acceptor acceptors: electron-transfer flavoprotein, phenylmethylsulfonyl fluoride, 2,6-dichlorophenolindophenol, phenazine methosulfate, methylene blue Homo sapiens crotonyl-CoA + CO2 + reduced acceptor
-
 ?
1.3.8.6 glutaryl-CoA + acceptor acceptors: electron-transfer flavoprotein, phenylmethylsulfonyl fluoride, 2,6-dichlorophenolindophenol, phenazine methosulfate, methylene blue Sus scrofa crotonyl-CoA + CO2 + reduced acceptor
-
 ?
1.3.8.6 glutaryl-CoA + electron-transfer flavoprotein
-
 Sus scrofa crotonyl-CoA + CO2 + reduced electron-transfer flavoprotein
-
 r
1.3.8.6 hexanoyl-CoA + acceptor
-
 Homo sapiens ? + reduced acceptor
-
 ?
1.3.8.6 hexanoyl-CoA + acceptor
-
 Sus scrofa ? + reduced acceptor
-
 ?
1.3.8.6 isovaleryl-CoA + acceptor
-
 Sus scrofa ? + reduced acceptor
-
 ?
1.3.8.6 octanoyl-CoA + acceptor
-
 Sus scrofa ? + reduced acceptor
-
 ?

Subunits

EC Number Subunits Comment Organism
1.3.8.6 tetramer 4 * 47000, SDS-PAGE Sus scrofa
1.3.8.6 tetramer 4 * 58800, SDS-PAGE Homo sapiens

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.3.8.6 5.45
-
 glutaryl-CoA
-
 Sus scrofa
1.3.8.6 14.3
-
 electron-transfer flavoprotein
-
 Sus scrofa

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.8.6 FAD
-
 Homo sapiens
1.3.8.6 FAD
-
 Sus scrofa