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Literature summary extracted from
- 2,4-Diaminopentanoic acid C4 dehydrogenase, purification and properties of the protein (1973), J. Biol. Chem., 247, 385-388.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.4.1.12 | 5,5'-dithiobis(2-nitrobenzoate) | - |
Acetoanaerobium sticklandii |  |
| 1.4.1.12 | iodoacetate | - |
Acetoanaerobium sticklandii | |
| 1.4.1.12 | N-ethylmaleimide | - |
Acetoanaerobium sticklandii | |
| 1.4.1.12 | p-chloromercuribenzoate | - |
Acetoanaerobium sticklandii | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.4.1.12 | 35400 | - |
2 * 35400 SDS-PAGE, sedimentation centrifugation in 6 M guanidine-HCl | Acetoanaerobium sticklandii |
| 1.4.1.12 | 40000 | - |
2 * 40000 SDS-PAGE, gel electrophoresis | Acetoanaerobium sticklandii |
| 1.4.1.12 | 72000 | 80000 | sedimentation equilibrium centrifugation | Acetoanaerobium sticklandii |
| 1.4.1.12 | 80000 | - |
gel electrophoresis | Acetoanaerobium sticklandii |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.4.1.12 | 2,4-diaminopentanoate + H2O + NAD(P)+ | Acetoanaerobium sticklandii | - |
2-amino-4-oxopentanoate + NH3 + NAD(P)H | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.4.1.12 | Acetoanaerobium sticklandii | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.4.1.12 | - |
Acetoanaerobium sticklandii |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.4.1.12 | 272.5 | - |
- |
Acetoanaerobium sticklandii |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.4.1.12 | 2,4-diaminopentanoate + H2O + NAD(P)+ | - |
Acetoanaerobium sticklandii | 2-amino-4-oxopentanoate + NH3 + NAD(P)H | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.4.1.12 | dimer | 2 * 35400 SDS-PAGE, sedimentation centrifugation in 6 M guanidine-HCl | Acetoanaerobium sticklandii |
| 1.4.1.12 | dimer | 2 * 40000 SDS-PAGE, gel electrophoresis | Acetoanaerobium sticklandii |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.4.1.12 | NAD+ | - |
Acetoanaerobium sticklandii | |
| 1.4.1.12 | NADP+ | - |
Acetoanaerobium sticklandii | |
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Release 2023.1 (January 2023)
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