EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.5.1.3 | 5,5'-dithiobis(2-nitrobenzoate) | - |
Daucus carota | |
1.5.1.3 | aminopterin | - |
Daucus carota | |
1.5.1.3 | methotrexate | - |
Daucus carota | |
1.5.1.3 | N-ethylmaleimide | - |
Daucus carota | |
1.5.1.3 | N10-formylaminopterin | - |
Daucus carota | |
1.5.1.3 | p-hydroxymercuribenzoate | - |
Daucus carota |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.5.1.3 | 45000 | - |
enzyme complex with dihydrofolate reductase activity, thymidylate synthase activity and three other polypeptides of unknown function, dihydrofolate reductase subunit, SDS-PAGE | Daucus carota |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.5.1.3 | Daucus carota | - |
wild carrot, enzyme complex with dihydrofolate reductase activity, thymidylate synthase activity and three other polypeptides of unknown function | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.5.1.3 | enzyme complex with dihydrofolate reductase activity, thymidylate synthase activity and three other polypeptides of unknown function | Daucus carota |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.5.1.3 | 10.8 | - |
purified enzyme | Daucus carota |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.5.1.3 | More | enzyme complex with dihydrofolate reductase activity, thymidylate synthase activity and three other polypeptides of unknown function, 286000 MW complex, 45000 MW dihydrofolate reductase subunit and 4 other polypeptide chains: 95000, 70000, 50000, 26000 | Daucus carota |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
1.5.1.3 | 42 | - |
assay at | Daucus carota |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
1.5.1.3 | additional information | - |
assay at pH 7.2, no activity at pH 5.9 | Daucus carota |