Any feedback?
Literature summary extracted from
- Thioredoxin and thioredoxin reductase in pancreatic islets may participate in diabetogenic free-radical production (1982), Biochem. Biophys. Res. Commun., 107, 1412-1418.
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.8.1.9 | thioredoxin + NADP+ | Escherichia coli | - |
thioredoxin disulfide + NADPH | - |
? |  |
| 1.8.1.9 | thioredoxin + NADP+ | Mus musculus | reduction of free radicals at the surface of the epidermis, enzyme may play a role in physiology of pancreatic beta-cells | thioredoxin disulfide + NADPH | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.8.1.9 | Bos taurus | - |
- |
- |
| 1.8.1.9 | Escherichia coli | - |
- |
- |
| 1.8.1.9 | Mus musculus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.8.1.9 | pancreatic islet | - |
Mus musculus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.8.1.9 | additional information | - |
- |
Mus musculus |
| 1.8.1.9 | additional information | - |
- |
Escherichia coli |
| 1.8.1.9 | additional information | - |
- |
Bos taurus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.8.1.9 | 5,5'-dithiobis(2-nitrobenzoic acid) + NADPH | i.e. DTNB | Mus musculus | 2-nitro-5-thiobenzoate + NADP+ | - |
? | |
| 1.8.1.9 | 5,5'-dithiobis(2-nitrobenzoic acid) + NADPH | i.e. DTNB | Escherichia coli | 2-nitro-5-thiobenzoate + NADP+ | - |
? | |
| 1.8.1.9 | 5,5'-dithiobis(2-nitrobenzoic acid) + NADPH | i.e. DTNB | Bos taurus | 2-nitro-5-thiobenzoate + NADP+ | - |
? | |
| 1.8.1.9 | 5,5'-dithiobis(2-nitrobenzoic acid) + NADPH | requires thioredoxin for reduction of DTNB | Mus musculus | 2-nitro-5-thiobenzoate + NADP+ | - |
? | |
| 1.8.1.9 | 5,5'-dithiobis(2-nitrobenzoic acid) + NADPH | requires thioredoxin for reduction of DTNB | Escherichia coli | 2-nitro-5-thiobenzoate + NADP+ | - |
? | |
| 1.8.1.9 | alloxan + NADPH | - |
Mus musculus | ? | - |
? | |
| 1.8.1.9 | alloxan + NADPH | - |
Escherichia coli | ? | - |
? | |
| 1.8.1.9 | alloxan + NADPH | - |
Bos taurus | ? | - |
? | |
| 1.8.1.9 | thioredoxin + NADP+ | - |
Mus musculus | thioredoxin disulfide + NADPH | - |
ir | |
| 1.8.1.9 | thioredoxin + NADP+ | - |
Escherichia coli | thioredoxin disulfide + NADPH | - |
? | |
| 1.8.1.9 | thioredoxin + NADP+ | - |
Escherichia coli | thioredoxin disulfide + NADPH | - |
ir | |
| 1.8.1.9 | thioredoxin + NADP+ | - |
Bos taurus | thioredoxin disulfide + NADPH | - |
ir | |
| 1.8.1.9 | thioredoxin + NADP+ | reduction of free radicals at the surface of the epidermis, enzyme may play a role in physiology of pancreatic beta-cells | Mus musculus | thioredoxin disulfide + NADPH | - |
? | |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.8.1.9 | NADPH | - |
Mus musculus | |
| 1.8.1.9 | NADPH | - |
Escherichia coli | |
| 1.8.1.9 | NADPH | - |
Bos taurus | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
