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Literature summary extracted from

  • Hansbrough, J.R.; Takahashi, Y.; Ueda, N.; Yamamoto, S.; Holtzman, M.J.
    Identification of a novel arachidonate 12-lipoxygenase in bovine tracheal epithelial cells distinct from leukocyte and platelet forms of the enzyme (1990), J. Biol. Chem., 265, 1771-1776.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.13.11.31 cytosol
-
 Bos taurus 5829
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.13.11.31 72000
-
 x * 72000, SDS-PAGE Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.31 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.13.11.31 leukocyte
-
 Bos taurus
-
1.13.11.31 tracheal epithelium
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.13.11.31 0.3
-
 epithelial enzyme Bos taurus
1.13.11.31 0.7
-
 leukocyte enzyme Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.31 11,14,17-eicosatrienoic acid + O2
-
 Bos taurus ?
-
 ?
1.13.11.31 11,14-eicosadienoic acid + O2
-
 Bos taurus ?
-
 ?
1.13.11.31 4,7,10,13,16,19-docosahexaenoic acid + O2
-
 Bos taurus ?
-
 ?
1.13.11.31 5,8,11,14,17-eicosapentaenoic acid + O2
-
 Bos taurus 12-hydroxy-5,8,10,14,17-eicosapentaenoic acid
-
 ?
1.13.11.31 8,11,14-eicosatrienoic acid + O2 dihomo-gamma-linolenic acid Bos taurus 12-hydroxyeicosatrienoic acid
-
 ?
1.13.11.31 alpha-linolenic acid + O2
-
 Bos taurus ?
-
 ?
1.13.11.31 arachidonate + O2 i.e. 5Z,8Z,11Z,14Z-eicosatetraenoic acid Bos taurus (5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate
-
 ?
1.13.11.31 gamma-linolenic acid + O2 i.e. 6,9,12-octadecatrienoic acid Bos taurus 10-hydroxy-octadeca-6Z,8E,12Z-trienoic acid
-
 ?
1.13.11.31 linoleic acid + O2 i.e. 9,12-octadecadienoic acid Bos taurus 13(S)-hydroperoxy-9Z,11E-octadecadienoic acid
-
 ?

Subunits

EC Number Subunits Comment Organism
1.13.11.31 ? x * 72000, SDS-PAGE Bos taurus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.13.11.31 7.4 8
-
 Bos taurus