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Literature summary extracted from

  • Denner, L.A.; Wei, S.C.; Lin, H.S.; Lin, C.T.; Wu, J.Y.
    Brain L-glutamate decarboxylase: purification and subunit structure (1987), Proc. Natl. Acad. Sci. USA, 84, 668-672.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.15 2-oxoglutarate
-
 Rattus norvegicus
4.1.1.15 3-Mercaptopropionic acid
-
 Rattus norvegicus
4.1.1.15 5,5'-dithiobis(2-nitrobenzoate)
-
 Rattus norvegicus
4.1.1.15 aminooxyacetic acid
-
 Rattus norvegicus
4.1.1.15 beta-Methylene-DL-Asp
-
 Rattus norvegicus
4.1.1.15 NaCl
-
 Rattus norvegicus
4.1.1.15 Zinc acetate
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.15 1.59
-
 L-Glu
-
 Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.1.15 40000
-
 x * 40000, SDS-PAGE in presence of 4 M urea and 2-mercaptoethanol Rattus norvegicus
4.1.1.15 40000
-
 x * 40000 + x * 80000, SDS-PAGE Rattus norvegicus
4.1.1.15 80000
-
 x * 40000 + x * 80000, SDS-PAGE Rattus norvegicus
4.1.1.15 110000
-
 gel filtration Rattus norvegicus
4.1.1.15 120000
-
 gradient PAGE Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.15 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.15
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.15 brain
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.1.1.15 additional information
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.15 L-Glu
-
 Rattus norvegicus 4-Aminobutanoate + CO2
-
 ?

Subunits

EC Number Subunits Comment Organism
4.1.1.15 ? x * 40000, SDS-PAGE in presence of 4 M urea and 2-mercaptoethanol Rattus norvegicus
4.1.1.15 ? x * 40000 + x * 80000, SDS-PAGE Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.15 7.3
-
-
 Rattus norvegicus