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Literature summary extracted from

  • Eichler, W.
    Properties of purified L-ornithine decarboxylase (EC 4.1.1.17) from Tetrahymena thermophila (1989), J. Protozool., 36, 577-582.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.1.1.17 DNA stimulates Tetrahymena thermophila
4.1.1.17 heparin stimulates Tetrahymena thermophila
4.1.1.17 RNA stimulates Tetrahymena thermophila

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.17 alpha-DL-difluoromethylornithine
-
Tetrahymena thermophila
4.1.1.17 putrescine slight Tetrahymena thermophila

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.17 0.11
-
L-Orn
-
Tetrahymena thermophila
4.1.1.17 0.17
-
L-Orn
-
Tetrahymena thermophila

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.1.17 68000
-
gel filtration Tetrahymena thermophila

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.17 Tetrahymena thermophila
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.17
-
Tetrahymena thermophila

Storage Stability

EC Number Storage Stability Organism
4.1.1.17 stable at 0°C Tetrahymena thermophila

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.17 L-Orn
-
Tetrahymena thermophila Putrescine + CO2
-
?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
4.1.1.17 37
-
1 h, 14% loss of activity Tetrahymena thermophila

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.17 6 7
-
Tetrahymena thermophila

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.1.17 pyridoxal 5'-phosphate Km: 0.00023 mM Tetrahymena thermophila