EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.17.4.2 | 5'-deoxyadenosylcobalamin | - |
Thermoplasma acidophilum | |
1.17.4.2 | 5'-deoxyadenosylcobalamin | - |
Lactobacillus leichmannii |
EC Number | Cloned (Comment) | Organism |
---|---|---|
1.17.4.2 | chromosomal DNA containg RNR gene PCR amplified, gene cloned, completely sequenced and expressed in Escherichia coli | Thermoplasma acidophilum |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.17.4.2 | 100000 | - |
size exclusion chromatography, SDS-PAGE | Thermoplasma acidophilum |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | Thermus aquaticus | - |
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | Escherichia coli | - |
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | Homo sapiens | - |
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | Halobacterium salinarum | - |
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | Haloferax volcanii | - |
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | Thermoplasma acidophilum | - |
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | Mycobacterium tuberculosis | - |
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | Anabaena sp. | - |
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | Lactobacillus leichmannii | - |
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | Thermus aquaticus X1 | - |
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.17.4.2 | Anabaena sp. | - |
- |
- |
1.17.4.2 | Escherichia coli | - |
- |
- |
1.17.4.2 | Halobacterium salinarum | - |
- |
- |
1.17.4.2 | Haloferax volcanii | - |
- |
- |
1.17.4.2 | Homo sapiens | - |
human | - |
1.17.4.2 | Lactobacillus leichmannii | - |
- |
- |
1.17.4.2 | Mycobacterium tuberculosis | - |
- |
- |
1.17.4.2 | Thermoplasma acidophilum | - |
DSM 1728 | - |
1.17.4.2 | Thermus aquaticus | - |
- |
- |
1.17.4.2 | Thermus aquaticus X1 | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.17.4.2 | - |
Thermoplasma acidophilum |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.17.4.2 | 0.0018 | - |
- |
Thermoplasma acidophilum |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Thermus aquaticus | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Escherichia coli | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Homo sapiens | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Halobacterium salinarum | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Haloferax volcanii | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Thermoplasma acidophilum | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Mycobacterium tuberculosis | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Anabaena sp. | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Lactobacillus leichmannii | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Thermus aquaticus X1 | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | - |
Thermus aquaticus | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | - |
Escherichia coli | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | - |
Homo sapiens | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | - |
Halobacterium salinarum | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | - |
Haloferax volcanii | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | - |
Thermoplasma acidophilum | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | - |
Mycobacterium tuberculosis | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | - |
Anabaena sp. | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | - |
Lactobacillus leichmannii | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | - |
Thermus aquaticus X1 | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
1.17.4.2 | 55 | - |
- |
Thermoplasma acidophilum |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.17.4.2 | coenzyme B12 | - |
Thermoplasma acidophilum | |
1.17.4.2 | coenzyme B12 | - |
Mycobacterium tuberculosis | |
1.17.4.2 | coenzyme B12 | - |
Lactobacillus leichmannii |