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Literature summary extracted from

  • Lakshamanan, M.R.; Chansang, H.; Olson, J.A.
    Purification and properties of carotene 15,15-dioxygenase of rabbit intestine (1972), J. Lipid Res., 13, 477-482.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.13.11.63 1,10-phenanthroline
-
 Oryctolagus cuniculus
1.13.11.63 15,15'-Dehydro-beta-apo-10'-carotenol inhibits reaction with beta-apo-10'-carotenol Oryctolagus cuniculus
1.13.11.63 2,2'-dipyridyl
-
 Oryctolagus cuniculus
1.13.11.63 iodoacetamide
-
 Oryctolagus cuniculus
1.13.11.63 NEM
-
 Oryctolagus cuniculus
1.13.11.63 PCMB reversed by glutathione Oryctolagus cuniculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.13.11.63 0.067
-
 beta-apo-10'-carotenol + O2
-
 Oryctolagus cuniculus

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.63 Clarias batrachus
-
-
-
1.13.11.63 Domania subtryug
-
-
-
1.13.11.63 Gallus gallus
-
-
-
1.13.11.63 no activity in Felis catus
-
 intestine
-
1.13.11.63 Oryctolagus cuniculus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.13.11.63
-
 Oryctolagus cuniculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.13.11.63 intestine mucosa Gallus gallus
-
1.13.11.63 intestine mucosa Oryctolagus cuniculus
-
1.13.11.63 intestine mucosa Clarias batrachus
-
1.13.11.63 intestine mucosa Domania subtryug
-
1.13.11.63 intestine pylorus to the lower ileum Oryctolagus cuniculus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.13.11.63 0.000035
-
-
 Oryctolagus cuniculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.63 beta-apo-10'-carotenol + O2
-
 Oryctolagus cuniculus ?
-
 r

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.13.11.63 7.8
-
 reaction with beta-apo-10'-carotenol Oryctolagus cuniculus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
1.13.11.63 7 9 pH 7.0: about 50% of maximal activity, pH 9.0: about 35% of maximal activity, reaction with beta-apo-10'-carotenol Oryctolagus cuniculus