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Literature summary extracted from

  • Williard, D.E.; Nwankwo, J.O.; Kaduce, T.L.; Harmon, S.D.; Irons, M.; Moser, H.W.; Raymond, G.V.; Spector, A.A.
    Identification of a fatty acid DELTA6-desaturase deficiency in human skin fibroblasts (2001), J. Lipid Res., 42, 501-508.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.19.3 linoleic acid + AH2 + O2 Mus musculus DELTA6-desaturase reaction is the rate-limiting step in the conversion of linoleic acid and alpha linoleic acids to the longer, more highly unsaturated members of the n-6 and n-3 polyunsaturated fatty acids, metabolic pathway in mammalian cells gamma-linolenic acid + A + H2O
-
?
1.14.19.3 linoleic acid + AH2 + O2 Homo sapiens DELTA6-desaturase reaction is the rate-limiting step in the conversion of linoleic acid and alpha linoleic acids to the longer, more highly unsaturated members of the n-6 and n-3 polyunsaturated fatty acids, metabolic pathway in mammalian cells gamma-linolenic acid + A + H2O
-
?
1.14.19.3 linoleic acid + AH2 + O2 Rattus norvegicus DELTA6-desaturase reaction is the rate-limiting step in the conversion of linoleic acid and alpha linoleic acids to the longer, more highly unsaturated members of the n-6 and n-3 polyunsaturated fatty acids, metabolic pathway in mammalian cells gamma-linolenic acid + A + H2O
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.14.19.3 Homo sapiens
-
human
-
1.14.19.3 Mus musculus
-
-
-
1.14.19.3 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.19.3 brain
-
Homo sapiens
-
1.14.19.3 brain
-
Rattus norvegicus
-
1.14.19.3 cerebellum neurons Rattus norvegicus
-
1.14.19.3 fibroblast skin fibroblast Homo sapiens
-
1.14.19.3 retina
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.19.3 linoleic acid + AH2 + O2 DELTA6-desaturase reaction is the rate-limiting step in the conversion of linoleic acid and alpha linoleic acids to the longer, more highly unsaturated members of the n-6 and n-3 polyunsaturated fatty acids, metabolic pathway in mammalian cells Mus musculus gamma-linolenic acid + A + H2O
-
?
1.14.19.3 linoleic acid + AH2 + O2 DELTA6-desaturase reaction is the rate-limiting step in the conversion of linoleic acid and alpha linoleic acids to the longer, more highly unsaturated members of the n-6 and n-3 polyunsaturated fatty acids, metabolic pathway in mammalian cells Homo sapiens gamma-linolenic acid + A + H2O
-
?
1.14.19.3 linoleic acid + AH2 + O2 DELTA6-desaturase reaction is the rate-limiting step in the conversion of linoleic acid and alpha linoleic acids to the longer, more highly unsaturated members of the n-6 and n-3 polyunsaturated fatty acids, metabolic pathway in mammalian cells Rattus norvegicus gamma-linolenic acid + A + H2O
-
?
1.14.19.3 octadeca-9,12-dienoic acid + AH2 + O2
-
Homo sapiens gamma-linolenic acid + A + H2O
-
?
1.14.19.3 octadeca-9,12-dienoic acid + AH2 + O2
-
Rattus norvegicus gamma-linolenic acid + A + H2O
-
?