Literature summary extracted from

Schroder, G.; Unterbusch, E.; Kaltenbach, M.; Schmidt, J.; Strack, D.; De Luca, V.; Schroder, J.
Light-induced cytochrome P450-dependent enzyme in indole alkaloid biosynthesis: tabersonine 16-hydroxylase (1999), FEBS Lett., 458, 97-102.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.14.14.103	-	Catharanthus roseus

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
1.14.14.103	129000	-	SDS-PAGE	Catharanthus roseus

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.14.14.103	tabersonine + NADPH + H+ + O2	Catharanthus roseus	indole alkaloid synthesis	16-hydroxytabersonine + NADP+ + H2O	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.14.14.103	Catharanthus roseus	P98183	line CP3a	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.14.14.103	tabersonine + NADPH + H+ + O2	-	Catharanthus roseus	16-hydroxytabersonine + NADP+ + H2O	-	?
1.14.14.103	tabersonine + NADPH + H+ + O2	indole alkaloid synthesis	Catharanthus roseus	16-hydroxytabersonine + NADP+ + H2O	-	?

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.14.14.103	cytochrome P450	K	Catharanthus roseus

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Release 2023.1 (January 2023)