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Literature summary extracted from
- Phenol hydroxylase from yeast. Reaction with phenol derivatives (1978), J. Biol. Chem., 253, 8835-8841.
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.14.13.7 | 0.005 | - |
2-Fluorophenol | - |
Cutaneotrichosporon cutaneum |  |
| 1.14.13.7 | 0.008 | - |
3-Fluorophenol | - |
Cutaneotrichosporon cutaneum | |
| 1.14.13.7 | 0.012 | - |
catechol | - |
Cutaneotrichosporon cutaneum | |
| 1.14.13.7 | 0.017 | - |
4-Fluorophenol | - |
Cutaneotrichosporon cutaneum | |
| 1.14.13.7 | 0.03 | - |
NADPH | cosubstrate 3-fluorophenol | Cutaneotrichosporon cutaneum | |
| 1.14.13.7 | 0.032 | - |
resorcinol | - |
Cutaneotrichosporon cutaneum | |
| 1.14.13.7 | 0.039 | - |
4-Chlorophenol | - |
Cutaneotrichosporon cutaneum | |
| 1.14.13.7 | 0.04 | - |
NADPH | + 2-fluorophenol | Cutaneotrichosporon cutaneum | |
| 1.14.13.7 | 0.05 | - |
NADPH | + phenol or resorcinol | Cutaneotrichosporon cutaneum | |
| 1.14.13.7 | 0.055 | - |
3-chlorophenol | - |
Cutaneotrichosporon cutaneum | |
| 1.14.13.7 | 0.09 | - |
NADPH | + catechol | Cutaneotrichosporon cutaneum | |
| 1.14.13.7 | 0.1 | - |
NADPH | + 4-fluorophenol | Cutaneotrichosporon cutaneum | |
| 1.14.13.7 | 0.5 | - |
NADPH | + 4-chlorophenol | Cutaneotrichosporon cutaneum | |
| 1.14.13.7 | 0.6 | - |
NADPH | cosubstrate 3-chlorophenol | Cutaneotrichosporon cutaneum | |
| 1.14.13.7 | 0.7 | - |
NADPH | + 2-chlorophenol or 3-methylphenol | Cutaneotrichosporon cutaneum | |
| 1.14.13.7 | 0.8 | - |
NADPH | + 4-methylphenol | Cutaneotrichosporon cutaneum | |
| 1.14.13.7 | 1.3 | - |
NADPH | + 2-methylphenol | Cutaneotrichosporon cutaneum | |
| 1.14.13.7 | 1.7 | - |
NADPH | in the absence of a phenolic substrate | Cutaneotrichosporon cutaneum | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.13.7 | Cutaneotrichosporon cutaneum | - |
yeast | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.13.7 | 2-chlorophenol + O2 + NADPH | - |
Cutaneotrichosporon cutaneum | ? | - |
? | |
| 1.14.13.7 | 2-fluorophenol + O2 + NADPH | - |
Cutaneotrichosporon cutaneum | ? | - |
? | |
| 1.14.13.7 | 2-methyl-phenol + O2 + NADPH | - |
Cutaneotrichosporon cutaneum | ? | - |
? | |
| 1.14.13.7 | 3-chlorophenol + O2 + NADPH | - |
Cutaneotrichosporon cutaneum | ? | - |
? | |
| 1.14.13.7 | 3-fluorophenol + O2 + NADPH | - |
Cutaneotrichosporon cutaneum | ? | - |
? | |
| 1.14.13.7 | 3-methylphenol + O2 + NADPH | - |
Cutaneotrichosporon cutaneum | ? | - |
? | |
| 1.14.13.7 | 4-chlorophenol + O2 + NADPH | - |
Cutaneotrichosporon cutaneum | ? | - |
? | |
| 1.14.13.7 | 4-fluorophenol + O2 + NADPH | - |
Cutaneotrichosporon cutaneum | ? | - |
? | |
| 1.14.13.7 | 4-methyl-phenol + O2 + NADPH | - |
Cutaneotrichosporon cutaneum | ? | - |
? | |
| 1.14.13.7 | catechol + O2 + NADPH | - |
Cutaneotrichosporon cutaneum | ? | - |
? | |
| 1.14.13.7 | phenol + NADPH + O2 | - |
Cutaneotrichosporon cutaneum | catechol + NADP+ + H2O | - |
? | |
| 1.14.13.7 | resorcinol + NADPH + O2 | - |
Cutaneotrichosporon cutaneum | ? | - |
? | |
| 1.14.13.7 | various phenolic substrates + NADPH + H+ + O2 | - |
Cutaneotrichosporon cutaneum | ? | - |
? | |
Turnover Number [1/s]
| EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.14.13.7 | 2.08 | 11.5 | NADPH | value depends on phenolic substrate | Cutaneotrichosporon cutaneum | |
| 1.14.13.7 | 4.5 | 13.2 | various phenolic substrates | - |
Cutaneotrichosporon cutaneum |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.13.7 | NADPH | - |
Cutaneotrichosporon cutaneum | |
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