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Literature summary extracted from

  • Barclay, S.S.; Woodley, J.M.; Lilly, M.D.; Spargo, P.L.; Pettman, A.J.
    Production of cyclohexanone monooxygenase from Acinetobacter calcoaceticus for large scale Baeyer-Villiger monooxygenase reactions (2001), Biotechnol. Lett., 23, 385-388.
No PubMed abstract available

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.13.22 cyclohexanone + NADPH + O2 Acinetobacter calcoaceticus
-
 1-oxa-2-oxocycloheptane + NADP+ + H2O
-
 ?
1.14.13.22 additional information Acinetobacter calcoaceticus inductive growth on cyclohexanol, addition of cyclohexanone ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.22 Acinetobacter calcoaceticus
-
 NCIB 9871
-
1.14.13.22 Acinetobacter calcoaceticus
-
 inducible by cyclohexanone
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.14.13.22 industrial scale production Acinetobacter calcoaceticus

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.14.13.22 additional information
-
-
 Acinetobacter calcoaceticus

Storage Stability

EC Number Storage Stability Organism
1.14.13.22 -18°C, crude homogenates, negligible loss of activity, 2 months Acinetobacter calcoaceticus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.13.22 2-hexyl-cyclopentanone + NADPH + O2
-
 Acinetobacter calcoaceticus ?
-
 ?
1.14.13.22 4-methylcyclohexanone + NADPH + O2
-
 Acinetobacter calcoaceticus 1-oxa-2-oxo-5-methylcycloheptane + NADP+ + H2O
-
 ?
1.14.13.22 cyclohexanone + NADPH + O2
-
 Acinetobacter calcoaceticus 6-hexanolide + NADP+ + H2O product: epsilon-caprolactone i.e. 1-oxa-2-oxocycloheptane ?
1.14.13.22 cyclohexanone + NADPH + O2
-
 Acinetobacter calcoaceticus 1-oxa-2-oxocycloheptane + NADP+ + H2O
-
 ?
1.14.13.22 additional information inductive growth on cyclohexanol, addition of cyclohexanone Acinetobacter calcoaceticus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.13.22 CHMO
-
 Acinetobacter calcoaceticus