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Literature summary extracted from
- Catalysis of three sequential dioxygenase reactions by thymine 7-hydroxylase (1973), Arch. Biochem. Biophys., 159, 180-187.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.11.6 | 5-Formyluracil | competitive inhibitor with respect to 5-hydroxymethyluracil; competitive inhibitor with respect to thymine | Neurospora crassa |  |
| 1.14.11.6 | 5-Hydroxymethyluracil | competitive inhibitor against thymine, noncompetitive against oxygen | Neurospora crassa | |
| 1.14.11.6 | Uracil | inhibitor of the three reactions, 50% inhibition at 1 mM | Neurospora crassa | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.11.6 | Fe2+ | - |
Neurospora crassa | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.11.6 | Neurospora crassa | - |
- |
- |
| 1.14.11.6 | Neurospora crassa 1A | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.14.11.6 | - |
Neurospora crassa |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.14.11.6 | mycelium | - |
Neurospora crassa | - |
Temperature Stability [°C]
| EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 1.14.11.6 | 60 | - |
10% activity after 2 min | Neurospora crassa |
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Release 2023.1 (January 2023)
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